Welcome To Central Council for Research in Homoeopathy(CCRH)

Introduction

Dr. D. P. Rastogi Central Research Institute of Homoeopathy

Officer Incharge

Dr. Shaji Kumar

Address : Dr. D. P. Rastogi Central Research Institute of Homoeopathy

A-1/1, Sector 24, Gautam Buddh Nagar, Noida, Uttar Pradesh 201301

Phone No : 0120-2411323

Email Id : crihnoida[at]gmail[dot]com

ABDM ID : IN0910046455

Location :

About Us

a) About the Institute

Central Research Institute of Homoeopathy located at A-1/1, Sector 24, NOIDA, Uttar Pradesh is one of the premier research institutes of Central Council for Research in Homoeopathy, New Delhi under Ministry of AYUSH, Govt. of India, came into existence w.e.f 1st May, 2007.

It was named as Dr. D.P. Rastogi Central Research Institute of Homoeopathy on 7 ^th October 2015 and officially inaugurated by Shri Shripad Naik, Honble Minister of State (Independent charge), Ministry of AYUSH, Govt. of India.

Late Dr. D.P. Rastogi (1939-2010) was the Director of Central Council for Research in Homoeopathy, New Delhi from 1984-1999. His major contribution in the field of Homoeopathy started with the Formulation of Homoeopathic Central Council Act in 1973. He introduced Homoeopathy in Drug and Cosmetic Act and took initiatives for publication of Homoeopathic Pharmacopoeia of India. He was a passionate teacher, author, physician and researcher. He is also known as the Ambassador for Indian Homoeopathy and has been honoured with numerous awards, to name a few:

The Hahnemann Award in 1995
Dhanwantri Award in 1997
Hahnemann Memorial Award in 2002
The Lifetime Achievement Award in 2008

The institute has been established with its focus on research and engaged for overall development and promotion of Homoeopathic system of medicine through scientific research. There is full fledge hospital set up including OPD, IPD, Laboratory facilities along with speciality clinics viz. ENT, Ophthalmology, Physiotherapy, Lifestyle Disorder Clinic, Dermatology and Rheumatology clinics are running successfully within the institute. Apart from catering to the needs of the patients, the institute carries out research in the field of Drug Standardization, Drug Proving, Clinical Verification and Clinical Research.

The institute endeavours to keep pace with the time and conduct research on the scientific parameters without deviating from the principles of homoeopathy, so that the results of these scientific studies may be used not only by the homoeopathic fraternity but the scientific world for the betterment of mankind as well.

Apart from the primary focus, the institute is also developing Resource Centre of Information on Homoeopathy.

b) Mandate of the Institute

To explore various homoeopathic research areas involving multi-disciplinary approach in the light of modern scientific parameters.
To standardize homoeopathic drugs in terms of their pharmacognostical, physico-chemical and pharmacological profiles for quality control of homoeopathic drugs.
To prove coded homoeopathic drugs on healthy human beings through double blind technique.
To clinically verify the pathogenesis of proved/partially proved homoeopathic drugs.
To work in the field of fundamental, applied and evidence based research areas to explore the possibilities of solution of problem related to potency and mechanism of action of homoeopathic drugs scientifically.
To collaborate with other Institutes (Homoeopathic and Allied) for taking up research projects and exchange information with other Institutions of Excellence for promotion of Homoeopathy.
To propagate research findings and awareness amongst the homeopathic fraternity in particular and masses in general; through books, monographs, journals, newsletter, I.E.C. Material, CME, audio visuals etc. through National Resource Centre, Public Information cell, Arogya melas, Awareness camps etc.
To make efforts for the capacity building of scientists, Para-medical staff, administrative staff by organizing and participating in the Continuing Medical Education, Workshops and Seminars at national and international level.
To provide effective and free health care services to the needy at grass root level through its regular OPDs, IPDs and health camps.

Staff Members

Regular Staff

S.No.	Name	Designation
1.	Dr.Shaji Kumar R.T.	AD(H)/Officer In-charge
2.	Dr. Padmalaya Rath	RO(H), S-4, Hospital In-charge
3.	Dr. Kumar Vivekanand	RO(H), S‐4 (Posted at BIS)
4.	Dr. Sonia Raizada	RO(H), S-2
5.	Dr.Meetu Geol	RO(H), S-2 (Posted at Min.of Ayush)
6.	Dr.Punam Kumari	RO(H), S-2
7.	Dr. Swapnil Kamble	RO(H), S-2
8.	Dr. Satvinder Singh	RO (Bio. Chem.), S-1
9.	Dr.Karanpreet Nahar	RO(H), S-1
10.	Dr. Harpreet Kaur	RO(H), S-1
11.	Dr. Shweta Gautam	RO(H), S-1
12.	Dr. Jyoti Sachdeva	RO(H), S-1
13.	Dr. Pankhuri Mishra	RO(H), S-1
14.	Dr. Radhika Agarwal	RO(H), S-1
15.	Dr. Swati Pandey	RO(H), S-1
16.	Mrs.Nishi Sanoj	Staff Nurse
17.	Mrs.Mercy Madhulatha	Staff Nurse
18.	Mrs.Rajni Tirkey	Staff Nurse
19.	Mrs.Manju Vijesh	Staff Nurse
20.	Mrs.Kimneilhing Gangte	Staff Nurse
21.	Mrs.Rashmi Jha	Hindi Asstt.
22.	Dr. Kirti Singh	Junior Librarian
23.	Sh. Anil Kumar	Pharmacist
24.	Sh. Gurjeet Singh	Lab.Tech
25.	Mrs. Sonia Arora	Ultrasonography Technician
26.	Sh. Amit Kumar Sharma	X‐Ray Tech.
27.	Sh. Nikhil Tomar	UDC
28.	Sh. Kripa Shanker	UDC
29.	Sh. Ajay Srivastava	Phar.Asst.
30.	Sh. Parun Gautam	UDC
31.	Sh. Suresh Kumar	RCTO
32.	Sh. Rakesh Kumar	Plumber
33.	Sh. Vinod Kumar	Dark Room Asstt.
34.	Sh. Arun Kumar	UDC
35.	Sh. Nazim Ali	LDC
36.	Sh. Virendra Kumar	Cook
37.	Sh. Sushil Kumar	Kitchen Servant
38.	Sh. Surendra Pratap Singh	Kitchen Servant
	DS SECTION
39.	Dr. Pankaj Gupta	AD (Pharmacology)
40.	Dr.Binit Dwivedi	Ro(H) S‐3
41.	Dr. Satish Patel	ARo (Pharmacognosy)
42.	Mrs.Anamika Kotiya	Pharmacist

7. Contractual Staff

S.No.	Name	Designation
1.	Dr. Mahima Sharma	RA(Pharmacology)
2.	Sh. Raj Kumar Regar	RA(Microbiology)
3.	Dr. Shilpi Singh	RA (Botany)
4.	Dr. Insha Mir	RA (Vet.)
5.	Dr. Rakhi Mishra	RA (Chemistry)
6.	Dr. Tushita	Consultant (H)
7.	Dr. Bhawna Rastogi	SRF(H)
8.	Dr. Meenakshi	SRF(H)
9.	Dr. Kruti saraswat	SRF(H)
10.	Dr. Yogyita	SRF(H)
11.	Dr. Shree Nigam	SRF(H)
12.	Dr. Shweta Singh	SRF(H)
13.	Dr. Abhilasha Bhati	SRF(H)
14.	Dr. Purnima	SRF(H)
15.	Dr. Nizamuddin	SRF(H)
16.	Dr. Shashi	JRF(H)
17.	Dr. Neha	SRF(H)
18.	Dr. Varsha	SRF(H)
19.	Dr. Riya	SRF(H)
20.	Dr. Priya	SRF(H)
21.	Dr. Akansha	SRF(H)
22.	Dr. Shabiha	JRF(H)
23.	Ms. Anu Verma	SRF (Bot.)
24.	Dr.Mahima Chaudhary	JRF(H)
25.	Ms. Sangeeta	JRF (Life Sc.)
26.	Ms. Anamika Maurya	JRF (Bot.)
27.	Ms. Shaheen Zabbar	JRF (Pharm.)
28.	Ms. Tanvi Sharma	JRF (Micro Bio.)
29.	Dr. Sumaiya Alvi	JRF (Pharm.)
30.	Ms. Pragati Rathore	JRF (Chem.)
31.	Ms. Pallavi	JRF (Chem.)
32.	Mrs. Nisha Kumari	Staff Nurse
33.	Mrs. Kavita Dayal	Pharmacist
34.	Ms. Ruby	Pharmacist
35.	Ms. Nadira	Pharmacist
36.	Mrs. Jagriti	Lab Tech
37.	Sh Anupam Gupta	Lab Tech
38.	Sh. Anmol Bodh	Lab Tech
39.	Mrs. Puja	Lab Tech
40.	Sh. Arjun Kaushik	Office Asst.
41.	Mrs. Mamta Sharma	Office Asst.
42.	Sh. Abhay Bansal	Office Asst.
43.	Mrs. Priyanka Kaushik	Office Asst.
44.	Ms. Nidhi Shukla	Office Asst.
45.	Mrs. Aprita Dua	Office Asst.
46.	Sh. Pankaj Kumar	Office Asst.
47.	Mrs. Isha Kardam	Office Asst.
48.	Mr. Mahesh	Office Asst.
49.	Mrs. Reena	Lab Asst
50.	Mr. Subhash	Lab Asst
51.	Sh. Ali Mohd.	Ph. Assistant
52.	Mrs. Sunita	Cook
53.	Sh. Vicky Singh	Driver
54.	Ms. Neha Bisht	MTS
55.	Sh. Manish Kr. Singh	MTS
56.	Sh. Ashish Kumar	MTS
57.	Sh. Shivam Verma	MTS
58.	Sh. Jitendra	MTS
59.	Sh. Abhishek	MTS
60.	Sh. Sanjeev Tripathi	Security Guard
61.	Sh. Ajay Kumar	Security Guard
62.	Sh. Rajesh Kumar	Security Guard
63.	Sh. Lavkush Dwivedi	Security Guard
64.	Sh. Saddam	Security Guard
65.	Sh. Sumit	Security Guard
66.	Mrs. Ritu	Aya
67.	Mrs. Dharmawati	Aya
68.	Mrs. Mumnaz	Aya
69.	Mrs. Sulochana Bist	Aya
70.	Mrs. Rita	Aya
71.	Mrs. Jyotsana	Aya
72.	Sh. Balkishan Pathak	Ward Boy
73.	Sh. Ramesh Kumar	Ward Boy
74.	Sh. Shatrohan Lal	Ward Boy
75.	Sh. Ashok Kumar	Ward Boy
76.	Sh. Vikram Chand	Ward Boy
77.	Sh. Arman	Ward Boy
78.	Sh. Ravi Lal	Safaiwala
79.	Sh. Prince	Safaiwala
80.	Sh. Mohar Singh	Safaiwala
81.	Sh. Om Prakash	Safaiwala
82.	Sh. Virendra Singh	Safaiwala
83.	Sh. Ram Kumar	Safaiwala
84.	Sh. Rakesh kumar	Safaiwala
85.	Sh. Alauddin	Mali
86.	Sh. Dushyant Joshi	Animal Attendant.
87.	Sh. Anuj Kumar	Animal Attendant
88.	Mrs. Ruby	Lab. Attendant
89.	Sh. Anuj	Lab. Attendant
	Consultants
103	Dr. Rajat Rashmi	Pharma.
104	Dr. Arun Garg	ENT
105	Dr. Anandiya	Eye
106	Dr. Meenu	Pathology Lab.
107	Dr. R.K.Saxena	Pathology Lab.
108	Dr. Sachin	Physiotherapy
109	Dr. Shashi lata	Physiotherapy

Research Studies

Ongoing Studies

RESEARCH ACTIVITIES OF THE INSTITUTE:

Drug standardization program: (NABL Accredited)

Standardization work of allotted drugs

DDPRCRI(H) Noida has contributed in laying down the pharmacognostic, physico-chemical and pharmacological standards of homoeopathic drugs from herbal, chemical and animal sources for manufacturing purpose. The Council has undertaken pharmacognostical studies on 317 drugs, physico-chemical studies on 336 drugs and pharmacological studies on 151 drugs. 149 drugs have been studied in all three aspects. The drug standardization data are provided to the Homoeopathic Pharmacopoeia Committee for inclusion in the Homoeopathic Pharmacopoeia of India, a reference book used by the homoeopathic industry for manufacturing homoeopathic medicines.

Research Activities

Drug standardization department was established in 1979 at HPL Ghaziabad and shifted to DDPRCRIH, Noida in 2008. Since then, this department has developed pharmacopoeial standards of pharmacognostical and physico-chemical parameters of 202 drugs. Later on, state of art research labs viz., Pharmacognosy, Physico-Chemical, Pharmacology, Molecular biology, Microbiology, Zebrafish lab, In-house Pharmacy lab and Animal house as per CPCSEA norms have also been developed with modern Instrumentation facility. Since then, DDPRCRI(H) contributed a lot in different research programs in every area of research be it pharmacognosy, physio-chemical, pharmacology or microbiology to achieve the mandate.

Research projects completed

● Evaluation of antifungal activity of certain homoeopathic medicines on the growth of human pathogenic fungi “Candida albicans” using In-vitro assays

● Evaluation of antifungal activity of certain homoeopathic medicines on the growth of human pathogenic fungi “Microsporum canis” using In-vitro assays.

● Evaluation of antifungal activity of certain homoeopathic medicines on the growth of human pathogenic fungi “Aspergillus niger” using In-vitro assays

● Screening of antibacterial activity of certain homoeopathic medicines on the growth of human pathogenic Gram negative bacterial strain Escherichia coli using in-vitro model.

● Screening of antibacterial activity of certain homoeopathic medicines on the growth of human pathogenic Gram negative bacterial strains Klebsiella pneumoniae using in-vitro models

● Screening of antibacterial activity of certain homoeopathic medicines on the growth of human pathogenic Gram negative bacterial strains Proteus mirabilis using in-vitro models

● Comparative Evaluation of Anti-Convulsant Potential of Homeopathic dilutions of Cuprum metallicum Prepared by Two Different Methods of Potentization in Zebrafish

● Study on Antimicrobial effect of Homoeopathic Medicinal Plant Fagopyrum Esculentum Moench has been completed

● Assessment of Biological Effect of Zincum Met New and old Potencies against the Fungal Strain has been completed

● Evaluation of Safety of Homoeopathic medicines (Alfa-Alfa, Avena sativa and Alfa-Avena Bioceutical) in rats

● Pilot study of standardisation of high fat diet + STZ induced diabetic nephropathy in experimental animals.

● In Vitro and In Vivo antifungal activities of selected homeopathic medicine and their effect on fungal cell wall integrity

● Evaluation of Pharmacological effect of homoeopathic drugs in Zebrafish Models”

● Evaluation of safety of homeopathic mother tinctures and their potencies on zebrafish embryonic development”.

● Safety Evaluation of Homeopathic Medicines in Acute Oral and Sub-acute Oral Toxicity Studies.

● Evaluation of immunomodulatory effect of Homoeopathic medicines on experimental animals.

● HPTLC Atlas of Homoeopathic Medicinal Plant Drugs Vol.1

● Collaboration work of H.P.I. and H.P. of United States

● Preparation of monographs of HPI vol. XI.

● Revision /upgradation of different volumes of Homoeopathic Pharmacopoeia of India (HPI).

● HPI (Homoeopathic Pharmacopoeia of India) REVISION WORK

● Estimation of Phytochemical Content, HPTLC Analysis and evaluation of Antioxidant Potential of Coffea cruda, Thuja occidentalis, Pyrus malus,Hydrastis canadensis and Thea chinensis mother tinctures and their

dilutions (6C, 12C, 30C and 200C) by Ultraviolet Spectroscopy.

● Comparative standardization study of Reserpine in Rauwolfia serpentina homoeopathic Mother Tinctures manufactured by different pharmaceutical industries using HPTLC.

● HPTLC Atlas of Medicinal Plant Drugs Used in Homoeopathy.

● Fundamental Homoeopathic Research (Drug Standardization) of

Adansonia digitata.

● Annual Assignments of each years

Ongoing Research Activities of Chemistry department

1. Annual assignment for the year 2023-24

2. Chemical profiling of exotic plants

3. Preparation of HPTLC Atlas of Homoeopathic Medicinal Plant Drugs Vol.3

4. Revision/Updation of Drug Standardization Vol.2,3 and 4

5. Homoeopathy sectional committee AYD 07

Ongoing Research Activities of Pharmacognosy department

· Macroscopic and microscopic Image Atlas for indigenous homoeopathic medicinal plants

· A Pilot Study on Standardization and Authentication of Homoeopathic Drugs by Using Molecular Methods

· Annual assignment for the year 2023-24

· Revision/Updation of Drug Standardization Vol.2,3 and 4

· BIS project

Ongoing Research Activities of Physico-Chemical department

● Chemical profiling of exotic plants

● Estimation of Phytochemical Content, HPTLC Analysis, FT-IR Analysis and evaluation of Antioxidant potential of Coffea cruda, Thuja occidentalis, Pyrusmalus, Hydrastis Canadensis and Thea chinensis mother tinctures and their dilutions (6C, 12C, 30C and 200C) by Ultra violet Spectroscopy method.

Ongoing Research Activities of Pharmacology department

● Evaluation of Antinociceptive and anti-inflammatory effect of homoeopathic medicines in adult zebrafish (Daniorerio)”

● Evaluation of safety of homeopathic mother tinctures in Albino rats.

● Microbial Standardization of Raw Plant Drug and Finished Product to Enhance the Quality of Homoeopathic drugs.

● Pharmacological investigation of selected homoeopathic medicine in complete Freund’s Adjuvant (CFA) induced arthritis in rats and explore possible mechanistic pathway

● Evaluation of effect of Homeopathic medicines on High-fat diet and streptozotocin-induced diabetic nephropathy in experimental rats”

● Isolation of drug resistance ESKAPE Pathogen from a urine sample and electron microscopic study to evaluate the effect of homoeopathic drugs on bacterial cell morpholog

Research projects in pipeline of Pharmacology Department

Investigating the Molecular Pathways of Homoeopathic Medicines in Zebrafish Model of Chronic Unpredictable Stress (CUS

Existing Infrastructure:

● Pharmacognosy laboratory

● Physico-chemical Laboratory

● Pharmacology Laboratory

● Microbiology Laboratory

● Molecular Biology Laboratory

● Zebrafish Laboratory

● In-House Pharmacy

● Animal House

● Raw Drug Museum

● Medicinal Plants Garden

Committees

CENTRAL RESEARCH INSTITUTE

Dr. D.P. RASTOGI CENTRAL RESEARCH INSTITUTE (H), NOIDA

Infrastructure

Services

Hospital Wing (NABH accredited hospital)- The interior of the institute is compartmentalized into various parts, including Outdoor and Indoor Patient Departments (OPD & IPD), Research and Development (R&D) Wing, Laboratories for various investigations.

Out-Patient Department (OPD)-The institute is running daily General OPDs and Research OPDs providing treatment to about 400-500 patients per day

Year wise status of patients attending OPD

Year

2011-12

2012-13

2013-14

2014-15

2015-16

2016-17

2017-18

2018-19

2019-20

2020-21

2021- 22

2022-23

2023-24

Apr- Nov 24

Dec 24- June 25

Total no. of patients

34107

102338

112245

109841

135240

146128

137385

112988

115776

51553

64605

111852

100788

○ 56330

56330

60,393

In-Patient Department (IPD)-The IPD wing of the institute started operating from 7^th August 2008. It has a provision of 35 beds, divided into male and female wards.

Year

2011-12

2012-13

2013-14

2014-15

2015-16

2016-17

2017-18

2018-19

2019-20

2020-21

Jan 22 to dec 22

Jan 23 to dec 23

Jan 24 to till date

(28.7.24)

29.07.24 to 30.11.24

1.12.24 to 30.06.25

Total no. of Beds

Total no. of IPD Cases

6756

5567

4961

4310

5197

4283

1891

1425

1992

194

3594

4785

2031

395

529

Specialty Clinics on

● ENT

● Ophthalmology

● Physiotherapy

● Dermatology

● Paediatric

● Lifestyle Disorders

● Geriatric

● Infertility

● Gynecology

● General & male Complaints

Laboratory Facilities -The Institute has functioning Pathology Laboratory, Biochemistry Laboratory with following test facility (Entry level NABL)

● Complete blood count.

● Diabetic profile, Lipid profile, Kidney Function Test, Liver Function Test, Serum Electrolytes (Na, K, Cl, Ca, Phos), Thyroid profile, Vitamin D3, Vitamin B-12.

● Rapid tests for RA factor, CRP, VDRL, Malaria, HbsAg, HCV, Dengue (NS1, IgM, IgG), Typhidot etc.

● Urine and Stool examinations (Routine Macroscopic and Microscopic Examinations)

● Hormonal Assessment

● Semen analysis

● UPT

Other Investigation facilities –

● Digital X-Ray

● Ultrasound

● ECG

Other facilities available

● Ambulance services (Patient transport services MOU has been done with ambulance services)

● Library

National Resource Centre (NRC)

Publication

Publications

The Institute has published 63 studies in national and international Journals since 2007

1. Binit Kumar Dwivedi, Sunil Kumar, C. Nayak and B.K. Mehta. Gas chromatography mass spectrometry (GC-MS)analysis of the hexane and benzene extracts of the Piper betle (leaf stalk) (Family: Piperaceae) from India. J. Med. Plants Res., 4(21) 2010: 2252-2255.

2. E. N. Sundaram, K .P. Singh, K. Pratap Reddy, Uma Maheswara Reddy, K.R.J. Nair, Ch. Raveendar and C. Nayak. A preliminary study to evaluate analgesic and behavioural activities of the homoeopathic drug, Anagalis arvensis in rats. Indian Journal of Research in Homoeopathy, 2010, 4(2):41- 48.

3. E. N. Sundaram, K .P. Singh, K. Pratap Reddy, Uma Maheswara Reddy, K. R. J. Nair, Ch. Raveendar and C. Nayak. Preliminary studies on analgesic and behavioural activities of the homeopathic formulations of Chenopodium ambrosioides in experimental animal models. Indian Journal of Research in Homoeopathy, 2010, 4(3):44-50.

4. E. N .Sundaram, K .P. Singh and Uma Maheswara Reddy. A comparative evaluation of medicinal plants for their hypoglycaemic activity in streptozotocin diabetic rats. Hamdard Medicus, 2010,53(4):5-14.

5. E. N. Sundaram, K .P. Singh, K. Pratap Reddy, Sunil Kumar, K. R. J. Nair, Anil Khurana, Hari Singh and C. Nayak. Indigofera tinctoria: preliminary experimental study evaluating its analgesic and behavioural activities in animals. Indian Journal of Research in Homoeopathy, 2010, 6(1&2):1-7

6. Quality assurance of Indian botanicals used in homoeopathy with pharmaco-anatomical profile of Oenothera biennis. Journal of Medicinal and Aromatic Plant Sciences.33(2):198-203,2011.

7. Binit Kumar Dwivedi, Sunil Kumar and E. N. Sundaram.. Physicochemical standardization of homoeopathic drug Buxus sempervirens. Proceeding of National seminar on “Recent Trends in Chemical and Biological Science” Dept. of Chemistry, Govt. Holkar Science College, Indore (M.P.), January 13 -15, 2012, P.28-30.

8. Binit Kumar Dwivedi, Sunil Kumar, Alok Kumar, Analysis of forskolin in Homoeopathic tinctures by validated HPLC method Int.J.Med.Arom.Plan. 2(1), 2012:195-199

9. E. N. Sundaram, K .P. Singh, Uma Maheswara Reddy. Hypoglycaemic activity of Indian medicinal plants in streptozotocin diabetic rats. Journal of Research and Education in Indian Medicine, 2012, 18(1):33 – 43

10. E. N. Sundaram, Kushal Pal Singh, Pratap Karnati Reddy, Kainikkara Raven Janardanan Nair, Anil Khurana, Hari Singh, Chaturbhuja Nayak.. An investigation to evaluate the analgesic and central nervous system depressant activities of Solanum nigrum L. in Homoeopathic potencies in experimental animal models. IJRH, 9(1):12-19. 2015

11. A. Rathi, D. Suresh Baburaj, E.N. Sundaram, Sunil Kumar, Anil Khurana, Raj K Manchanda. Pharmacognostic study of Chamaecyparis lawsoniana (Murr.) Parl.: A drug used in Homoeopathy. IJRH, 9(1):20-24.2015.

12. Gupta P, Sundaram EN, Dwivedi B, Changani S, Kaur H, Nayak D, Khurana A, Manchanda R. Evaluation of antifungal activity of homoeopathic medicines against human pathogenic fungi Candida albicans in-vitro MODEL. J Pharm Pharmacogn Res 3(suppl. 1): S189, 2015

13. Singh S, Gupta P, Khurana A, Gupta YK, Manchanda R. Evaluation of pharmacological screening and toxicity profile of selected homeopathic drugs.J Pharm Pharmacogn Res 3(suppl. 1): S25, 2015

14. Binit Kumar Dwivedi, Manoj Kumar, Anil Khurana, Bhopal Singh Arya, Echur Natrajan Sundaram, Raj K Manchanda “Comparative standardization study for determination of reserpine in Rauwolfia serpentina homoeopathic mother tinctures manufactured by different pharmaceutical industries using HPTLC as a check for quality control”, IJRH 2017, vol-11 (2), pp: 109-117.

15. Prajapati S, Sharma M, Gupta P, Kumar M, Dwivedi B, Arya BS. Evaluation of antifungal activity of different homoeopathic mother tinctures against Candida albicans. Indian J Res Homoeopathy; 2017;11:237-43

16. Rakhi Mishra, Manoj Kumar, Binit Dwivedi, B.S. Arya, Renu Arya. Anil Khurana and R.K. Manchanda, “Chemoprofiling of Homoeopathic drug Coffea Cruda” published in European Journal of Biomedical and Pharmaceutical Sciences on ISSN 2349-8870, Volume: 5, November Issue: 11 276-281, Year: 2018.

17. Gupta P, Sundaram EN, Sharma M, Prajapati S, Arya BS, Khurana A, et al. Pre-clinical pharmacology: An important aspect in homoeopathic research. Indian J Res Homoeopathy 2018;12:164-79.

18. Rakhi Mishra, Manoj Kumar, Binit Dwivedi, B.S. Arya, Renu Arya. Anil Khurana and R.K. Manchanda. Chemoprofiling of Homoeopathic drug Holarrhena antidysenterica Linn. f” published in Indian Journal of Research in Homoeopathy on ISSN 0974-7168, 12, 4, 2018-19.

19. Suneel Prajapati*, Shilpi Singh , Mahima Sharma, Arun Kumar, Digvijay Verma, Pankaj Gupta, Renu Arya, Bineet Dwivedi, Bhopal Singh Arya, Morphological Characterization of Homeopathic Medicinal Plants and Evaluation of their Biological Effect Against the Microsporumcanis. International Journal of Pharmacognosy and Phytochemical Research, April 2019.

20. Suneel Prajapati, Mahima Sharma, Arun Kumar, Pankaj Gupta, Binit Dwivedi, Bhopal Singh Arya, Renu Arya, Debadatta Nayak. Antimicrobial activity of different homoeopathic drugs and their potencies against ‘Aspergillusniger’ In-vitro. IJRH, September 2019

21. Rakhi Mishra, Manoj Kumar, Binit Dwivedi, B. S. Arya, Renu Arya, Anil Khurana, R.K. Manchanda “Importance of High Performance Thin Layer Chromatography and UV Spectroscopy in Analysis of Homoeopathic Drug Datura Ferox”. International Journal of Advances in Science, Engineering and Technology (IJASEAT). Volume-6, Issue-4, on 26th March 2019

22. Morpho-anatomical Observations on Homoeopathic Plant Drug Hygrophila spinosa T. Anderson; Pharmacognosy Journal, vol. 11, issue 2, Mar-Apr, 2019; Digvijay Verma, Shilpi Singh, Renu Arya, Soundararajan Rajan, Bhopal Singh Arya, Anil Khurana, and Raj Kumar Manchanda.

23. Binit Kumar Dwivedi et.al A Ready Reckoner of medicines in Homoeopathic Pharmacopoeia Book Published in 2019published by Central Council for Research in Homeopathy, Ministry of AYUSH, Government of India published on World Integrated Medicine Forum January 2019.

24. Megha Ranga, Binit Dwivedi, Renu Arya, Manoj, Anil Khurana. Qualitative analysis of Salvia sclarea (Clary Sage): A Homoeopathic medicinal plant. World Journal of Pharmacy and Pharmaceutical sciences. Volume 9, Issue 2, 901-912. ISSN 2278 – 4357.

25. S Prajapati, M Sharma, A Kumar, P Gupta, NK GV. An Update on Novel COVID-19 Pandemic; A Battle between Humans and Virus. Eur Rev Med PharmacolSci 2020; 24 (10): 5819-5829.

26. G.V. Narasimha Kumar, Arun Kumar, Mahima Sharma, Ashish Tripathi, Shilpi Singh, Digvijay Verma, Pankaj Gupta and Suneel Prajapati. Self-Protection of Medical Workers in Traditional Hospitals and Clinics against SARS-CoV-2 Infection”. Coronaviruses, 2020, 1, 1-5.

27. Suneel Prajapati, Aarti Bhardwaj,Pankaj Gupta. Antioxidant and anti-candida activity of selected medicinal plants of Indian origin. International journal edited by the Institute of Natural Fibres and Medicinal Plants. Vol. 66 No. 3 2020.

28. Suneel Prajapati, Aarti Bhardwaj, Pankaj Gupta. Anatomical And Phytochemical Standardization Of Terminalia Chebula And Syzygium Jambolanum: A Highly Used Medicinal Plant In India. Plant Cell Biotechnology and Molecular Biology 21(43&44):31-41; 2020

29. Binit Kumar Dwivedi, Manoj Kumar, Rakhi Mishra. “High-per High-performance thin-layer chromatography fingerprinting and antioxidant study of Mangiferaindica mother tincture”. Part of the Alternative and Complementary Medicine Commons. Published in Indian journal of Research in Homeopathy. 2021 Sep 29; 15(3):Article 2.

30. Binit Kumar Dwivedi, Manoj Kumar, Rakhi Mishra. Book Published: HPTLC Atlas of Medicinal Plant Drugs Used in Homoeopathy, ISBN : 9789381458709, published by Central Council for Research in Homeopathy, Ministry of AYUSH, Government of India published on World Homeopathy Day 10th April 2021, New Delhi, India.

31. SuneelPrajapati, Mahima Sharma, Arun Kumar, AshishTripathi, GV Narasimha Kumar, Shilpi Singh, Monika Singh, DigvijayVerma, Pankaj Gupta. AYUSH Preparations as Immunity Boosters in the Management of SARSCoV-2: A Review.Current Traditional Medicine, 2021, 7, 1-00

32. Sharma M, Prajapati S, Kumar A, Tripathi A, GVN Kumar, Gupta P. Safety Evaluation of Syzygium jambolanum on the Development of Zebrafish Embryos. Indian J of Pharmaceutical Education and Research. 2021;55(1):198-204.

33. Kumar GV, Chitra V, Gupta P, Biswas B, Arya R. Preclinical updates of the homoeopathic medicines used in diabetes mellitus: A narrative review. Indian J Res Homoeopathy 2021;15:31-40

34. Mahima Sharma, Suneel Prajapati, Arun Kumar, Ashish Tripathi, GV Narasimha Kumar, Pankaj Gupta. Effect of Acute Exposure of Belladonna Mother Tincture on Zebrafish Embryonic Development. Indian Journal of Pharmaceutical Sciences.2021; vol:83(5).

35. Singh T, Chhokar A, Thakur K, Aggarwal N, Pragya P, Yadav J, Tripathi T, Jadli M, Bhat A, Gupta P, Khurana A, Chandra Bharti A. Targeting Aberrant Expression of STAT3 and AP-1 Oncogenic Transcription Factors and HPV Oncoproteins in Cervical Cancer by Berberis aquifolium. Front Pharmacol. 2021 Oct 28;12:757414

36. Arun Kumar, Mahima Sharma, Suneel Prajapati and Pankaj Gupta. Adjuvant Approach to Mitigate the Adverse Effects of Cancer Treatments Using Homeopathic Medicines. Current Cancer Therapy Reviews. 2022; 18 (4): 252-261.

37. Arun Kumar, Suneel Prajapati, Mahima Sharma, Tejveer Singh, Neha Choudhary, Alok Bharti, Rohit Sharma, Pankaj Gupta. Quantitative Assessment of Antioxidant Potential of Selected Homeopathic Preparations in Clinical Practice. Drug Metabolism and Personalized Therapy. 2022;38 (2):179-190. doi: 10.1515/dmpt-2022-0169.

38. Determination of Digitoxin by Highperformance thin layer chromatography in Digitalis purpurea Rakhi MİSHRA1, 2, Binit DWİVEDİ2*, Deepshikha GUPTA Acta Pharm. Sci. Vol 60:(4), 2022

39. Standardization of homoeopathic drugs Vol-I (second revised edition) 2024: 1-205

40. Mishra, R. ., Dwivedi, B. ., & Gupta, D. (2022). Physicochemical, Phytochemical, Qualitative HPTLC and Antioxidant Study of Medicinal Plant Leucas aspera. Trends in Sciences, 19(16), 5646.

41. Verma D, Singh S, Patel S, Singh MP.Anatomical characterisation and foliar microscopy of Hypericum perforatum L. Indian Journal of Research in Homoeopathy 16 (1), 2022, 3.

42. Saka, V. P., Kumar, G. V. N., Goswami, A., Verma, D., & Gupta, P. (2023). Camphora Augments Humoral Mediated Immunity and Decreases Delayed type Hypersensitivity in BALB/c Mice: Immunomodulatory activity of Camphora in experimental mice. 23(1), 157–167. https://doi.org/10.18311/jnr/2023/31420

43. Lal, R., Sharma, M., Behera, S., Regar, R. K., Tripathi, D., Kumar, G. V. N., Singh, S., Verma, D., Gupta, P., Kaushik, S., & Khurana, A. (2023). Safety Evaluation of Arsenicum Album in Acute and Sub-Acute Toxicity Studies in Rats. Toxicology International, 30(2), 233–247.

44. Biswas B, Maity S, Sundaram EN, Kumar GV, Patel S. Physicochemical standardisation of the Homoeopathic drug, Apis mellifica: A preliminary attempt. Indian J Res Homoeopathy 2023;17:143-152.

45. Satish Patel, Shilpi Singh, Seema, Digvijay Verma. Foliar characterization of salparni – a remarkable medicinal plant. Vegetos, 2023. https://doi.org/10.1007/s42535-023-00748-5.

46. Published a monograph titled Dwivedi B, Verma D, Patel,S, Shashikanth J, Rajan S, Singh S,Mugendhiran S, Kumar M, Sharma R, Ephedra Vulgaris-Monograph,published by CCRH, New Delhi

47. Published a monograph titled Dwivedi B, Verma D, Patel,S, Shashikanth J, Rajan S, Singh S,Mugendhiran S, Kumar M, Mishra R, Syzygium jambolanum-Monograph, published by CCRH, New Delhi.

48. Published IS 18975:2024 Millefolium (Achillea Millefolium L.) whole plant for use in traditional medicine-specification by Bureau of Indian standards, New Delhi, 29 Nov. 2024 ICS 11.120.10.

49. Published IS 18977:2024 Millefolium (Achillea Millefolium L.) Hydro-alcohlic extract for use in Homeopathy-specification by Bureau of Indian standards, New Delhi, 29 Nov. 2024 ICS 11.120.10.

50. Published IS 18978:2024 alfalfa (Medicago sativa L.) for use in traditional medicine-specification by Bureau of Indian standards, New Delhi, 29 Nov. 2024 ICS 11.120.10.

51. Published IS 18979:2024 Withania somnifera Hydroalcohlic extract for use in Homeopathy-specification by Bureau of Indian standards, New Delhi, 29 Nov. 2024 ICS 11.120.10.

52. Sharma M, Behera S, Regar RK, Tripathi D, Singh S, Kumar NGV, Gupta P. Acute and Sub-acute Oral Toxicity Assessment of Ferrum phosphoricum in Rats. Homeopathy. 2024 May;113(2):86-97. doi: 10.1055/s-0043-1770338.

53. Behera Sangita, Sharma Mahima, Lal Roshan, Regar Raj Kumar, Tripathi Deepika, Gupta Pankaj*, Kumar G V Narasimha, Verma Digvijay, Kaushik Subhash and Khurana Anil, Investigation of The Effect of Metal-based Medicine Arsenicum album on Humoral Immune Response in SRBC-immunized Mice. Endocrine, Metabolic & Immune Disorders - Drug Targets 2024; 24(14):1622-1627

54. Goswami A, GV N, Saka V, Gupta P, Biswas B, Verma D. Safety of potentised dilutions of Rhus toxicodendron in Wistar albino rats. 2024;18:3-14.

55. Goswami A, Narasimha Kumar GV, Saka VP, Gupta P, Verma D. Safety Assessment of Ultra High Dilutions of Camphora officinarum: A Preclinical Investigation.. 2024 Jun;30(6):16-25

56. Saka VP, Kumar GVN, Goswami A, Sanapalli BKR, Gupta P, Verma D, Kaushik S. Modulatory action of Bryonia alba on the immune system in cyclophosphamide induced immunosuppression in BALB/c mice. PLoS One. 2024 Dec 31;19(12):e0309756.

57. Saka, V.P.; G. V., N.K.; Sanapalli, B.K.R.; Goswami, A.; Roy, A.; Agrawal, A.; Gupta, P.; Verma, D.; Kaushik, S. Unveiling the Immunostimulatory Potential of Rhus Toxicodendron in Immunocompromised Balb/C Mice Induced with Cyclophosphamide. Diseases 2024, 12, 178.

58. Binit Kumar, Rakhi Mishra, “Physicochemical, Phytochemical and Antioxidant Study of Pyrus Malus” Auctores 2025 https://doi.org/10.31579/2639-4162/256.

59. Satish Patel, Shilpi Singh, Seema, Digvijay Verma. Morphotaxonomical and anatomical characterization of Achillea millefolium L. :A therapeutics medicinal plant. Discover plants. 2025 2:212. https://doi.org/10.1007/s44372-025-00296-z.

60. Mahima Sharma, Sangita Behera, Rajkumar Regar, Pankaj Gupta, Godlaveti Vijay.Narsimha Kumar, Digvijay Verma, G.N.V. Satyanarayana, Devendra Kumar Patel. Safety Profile Of Matricaria Chamomilla: Insights From Zebrafish Embryo Development Toxicity Testing. Brazilian Journal of Pharmaceutical Sciences

61. Mahima Sharma, Vara Prasad Saka, Godlaveti Vijay Narasimha Kumar, Sangita Behera, Rajkumar Regar, Pankaj Gupta, Ritika H Narula. Evaluation of Safety and Efficacy of Cuprum metallicum in Zebrafish and Mouse models as a potential drug candidate for the management of seizures. Central Nervous System Agents in Medicinal Chemistry-2025 Feb 6.

62. Behera S, Sharma M, Regar RK, Gupta P, Jabbar S, Kumar GVN, Singh S. Immunomodulatory potential of phosphorus: insights from experimental mice models under normal and immunosuppressive condition. Drug Metab Pers Ther. 2025 Apr 28. doi: 10.1515/dmpt-2024-0103.

63. Raj Kumar Regar, Mahima Sharma, Sangita Behera, Pankaj Gupta, Roshan Lal, Suneel Prajapati, Arun Kumar, Godlaveti Vijay Narasimha Kumar, Vara Prasad Saka, Anurag Agrawal, Digvijay Verma, Subhash Kaushik, Exploring the therapeutic potential of Terminalia chebula against systemic candidiasis: An in vitro, in vivo, and in silico study, Fitoterapia, Volume 184, 2025, 106649

Poster presentations have been done for the following 07 studies:

Poster “Evaluation of developmental and behavioural fetal embryo toxicity (FET) of acute exposure of Syzygium jambolanum in zebrafish embryo: homeopathic remedy” for RANN-2018 at GLA University, Mathura conference
Poster “Effect of Lycopodium clavatum (Homeopathic drug) on Developmental and Behavioural Defects in Daniorerio embryo” for the NIPER university conference.
Poster presentation entitled “Antioxidant Potential and Antifungal Activity of Homeopathic Drug: Syzygium Jambolanum” for DDNPTM-2018 organised by NIPER, Mohali. Abstract accepted for poster presentation.
Poster entitled “Estimation of Phenolic Content and Antioxidant Potential of Homoeopathic Drugs to Elucidate Their Efficacy Mechanism” for NSMPH-2019 held on 23-24 March at CMPRH, Ooty.
Poster entitled “Safety evaluation of Acute Exposure of Artemisia vulgaris (ɸ) on Early Life Stage of Zebrafish Embryos Development” at NSMPH-2019, at Ooty.
Poster in International Convention on World Homoeopathy Day held at VigyanBhawan, New Delhi on 9th & 10th April 2016. BinitDwivedi, Manoj Kumar, Firdousmir, Pankaj Gupta, B.S.Arya E.N. Sundaram, Anil khurana and R.K.Manchanda “Standardization of Homoeopathic drug Curcuma longa”
Poster presentation at National Conference CPSBT-2018, NIPER Ahmedabad, entitled “A review on Zebrafish as an animal model in epilepsy a new era of translational research”.

9.2 Drug Proving Research Programme

Besides being the Nodal Office for Drug Proving since July 2014, this institute is one of the drug proving centers since 2007 which conducts Drug Proving Research Trials to record the signs and symptoms of coded drugs on healthy volunteers, in collaboration with Bakson Homoeopathic Medical College & Hospital, Greater Noida and Nehru Homoeopathic Medical College & Hospital, New Delhi. Since 2019, this center initiated a Drug Proving Research trial in collaboration with Dr. B. R. Sur Homoeopathic Medical College and Research Center, New Delhi.

Out of 125 drugs proved by the Council so far, 32 drugs have been proved and Sensitivity trial on 3 coded drugs is ongoing under this programme by the Institute. Research papers on 06 drugs have been published in Peer reviewed journal and proving data of 17 drugs (including the ones published in the journal as well) has been published in Drug Proving volumes 4, 5 and 6 books published by the Council. The details are as mentioned below:

9.2.1. Achievements

S. No.	Name of the study	Date of Initiation	Concluded	Status of study/publication
1.	Acorus calamus	2008-09	2009-10	Homoeopathic Drug Provings, 2019, Vol-6: 14-18.
2.	Cynara scolymus	2009-10	2010-11	Homoeopathic Drug Provings, 2011, Vol-4: 45-49.
3.	Foeniculum vulgare	2009-10	2010-11	Homoeopathic Drug Provings, 2013, Vol-5: 19-23.
4.	Cyclosporin	2009-10	2010-11	Homoeopathic Drug Provings, 2013, Vol-5: 15-18. A multi-centric double-blind homoeopathic pathogenetic trial of Cyclosporin. Indian J Res Homoeopathy 2013;7 (3):109-15.
5.	Hygrophilla spinosa	2010-11	2011-12	Homoeopathic Drug Provings, 2013, Vol-5: 31-38. A multi-centric double blind homoeopathic pathogenetic trial of Hygrophila spinosa. Indian J Res Homoeopathy 2014;8 (1):9-18.
6.	Magnolia grandiflora	2010-11	2011-12	Homoeopathic Drug Provings, 2013, Vol-5: 39-44. Homoeopathic drug proving of Mangolia grandiflora: A randomised double blind placebo-controlled trial. Indian J Res Homoeopathy 2019;13 (1):22-36.
7.	Azathioprine	2010-11	2011-12	Homoeopathic Drug Provings, 2013, Vol-5: 7-14.
8.	Allium sativum	2011-12	2012-13	Homoeopathic Drug Provings, 2013, Vol-5: 1-3. A multicentric, double-blind randomized, homoeopathic pathogenetic trial of Allium sativum. Indian J Res Homoeopathy 2016;10:6-23.
9.	Apium graveolens	2011-12	2012-13	Homoeopathic Drug Provings, 2019, Vol-6: 19-21.
10.	Avena sativa	2011-12	2012-13	Homoeopathic Drug Provings, 2013, Vol-5: 4-6.
11.	Leucas aspera	2012-13	2013-14	Homoeopathic Drug Provings, 2019, Vol-6: 41-43.
12.	Datura arborea	2012-13	2013-14	Homoeopathic Drug Provings, 2019, Vol-6: 28-30.
13.	Datura metal	2012-13	2013-14	Homoeopathic Drug Provings, 2019, Vol-6: 31-34.
14.	Withania somnifera	2012-13	2013-14	Homoeopathic pathogenetic trial of Withania somnifera: A multicentric, double-blind, randomised, placebo-controlled trial. Indian J Res Homoeopathy 2017;11 (2):97-108. Homoeopathic Drug Provings, 2019, Vol-6: 44-47.
15.	Brassica oleracea	2013-14	2014-15	Homoeopathic Drug Provings, 2019, Vol-6: 22-24.
16.	Ephedra valgaris	2013-14	2014-15	Homoeopathic Drug Provings, 2019, Vol-6: 35-37.
17.	Ferrum picricum	2013-14	2014-15	Homoeopathic Drug Provings, 2024, Vol-7: 30-34.
18.	Jalapa	2013-14	2014-15	Homoeopathic Drug Provings, 2019, Vol-6: 38-40.
19.	Syzigium jambolanum	2013-14	2014-15	Manuscript drafting under progress
20.	Benzenum nitricum	2013-14	2014-15	Manuscript drafting under progress
21.	Anthrakokali	2014-15	2015-16	Homoeopathic Drug Provings, 2024, Vol-7: 8-15.
22.	Blatta orientalis	2014-15	2015-16	Manuscript drafting under progress
23.	Cuprum aceticum	2014-15	2015-16	Homoeopathic pathogenetic trial of Cuprum aceticum: A multicentric, double-blind, randomized, placebo controlled trial. Indian J Res Homoeopathy 2021;15 (2):77-94.
24.	Justicia adhatoda	2015-16	2016-17	Proving data approved
25.	Solanum xanthocarpum	2015-16	2016-17	Proving data approved
26.	Gallicum acidum	2015-16	2016-17	2^nd draft of Manuscript undergoing review for the data analysis
27.	Damiana	2015-16	2016-17	Homoeopathic Drug Provings, 2024, Vol-7: 16-23.
28.	Oenothera biennis	2016-17	2017-18	Corrections in the 3^rd draft of Manuscript done
29.	Coleus forskohlii	2016-17	2017-18	Proving data approved
30.	Cimetidine	2017-18	2019-20	Manuscript drafting under progress
31.	Omeprazole	2017-18	2019-20	Manuscript drafting under progress
32.	Siegesbeckia orienatlis	2019-2020	2022-23	Proving data approved
33.	Drug code 143	2022-23	2023-24	Trial completed. Data analysis under progress
34.	Drug code 145	2024-25	Ongoing	Trial Completed. TME ongoing
35.	Drug code 146	2024-25	Ongoing	Near to Completion
36.	Drug Code 147	2024-25	Ongoing	Near to Completion
37.	Drug Code 148	2024-25	Ongoing	Fourth Quota ongoing

Other publications:

1. Manchanda RK, Khurana A, Fisher P, Arya BS, Mehra P, Saha S, et al. Homoeopathic drug proving researches (1996–2018): A scoping review. Indian J Res Homoeopathy 2020;14 (1):24-49.

2. Arya BS, Mehra P. Monograph on Homoeopathic Drug Hydrocotyle Asiatica. Central Council for Research in Homoeopathy, 2018: 17-24.

3. Manchanda RK, Khurana A, Mittal R, Mehra P, Taneja D, Nim P, Kashyap S. Drug Proving Training Module & Manual. Central Council for Research in Homoeopathy, 2016.

4. Siddiqui VA, Arya BS, Vichitra AK, Mittal R, Mehra P, Singh Vinay K. Monograph on Homoeopathic Drug Abroma augusta folia. Central Council for Research in Homoeopathy, 2018: 19-43.

5. Arya BS, Mittal R, Mehra P. Monograph on Homoeopathic Drug Cassia sophera. Central Council for Research in Homoeopathy, 2018: 15-30.

6. Siddiqui VA, Arya BS, Mittal R, Mehra P. Monograph on Homoeopathic Drug Atista indica. Central Council for Research in Homoeopathy, 2018: 25-35.

9.3Clinical Verification

Verification of drugs gives more reliability and helps us in creating an authentic Materia Medica. Central Council for Research in Homoeopathy has been conducting clinical verification studies of indigenous, rare and fragmentarily proved drugs since its inception in 1975. Some of these drugs were first proved by CCRH. Being a multicentric research study, DDPRCRIH, Noida has been a study site of clinical verification since 2007. 81 drugs have been clinically verified during this period which includes 60 drugs of plant origin, 06 drugs of animal origin, 13 drugs of chemical origin, 01 sarcode and 01 nosode. The Institute has contributed to the publication of the 1st, 2^nd, 3^rd, 4^th ,5^th and 6th volumes of the book ‘Study of Homoeopathic medicines through clinical verification – A new perspective’ which contains clinical verification data of 124 drugs.

Concluded study:

1. Clinical verification of 34 drugs

2. Clinical verification of 23 drugs: Study of Homoeopathic medicine through Clinical verification, Vol. 5

3. Clinical verification of 16 drugs: Manuscript submitted for publication.

4. Clinical verification of 08 drugs: Data verification and manuscript preparation going on

Ongoing/ assigned: Clinical verification of 10 homoeopathic drugs- A multi-centric prospective interventional single arm clinical trial: To be initiated

9.3.1. Research Achievements as peer reviewed journal publications:

1. Gupta J, Azis SP, Rutten L, Manchanda RK, Pramanik A, Chakraborty P, et al. Exploring the predictive value of specific symptom as prognostic factor: Assessment of group‑confined likelihood ratio for symptom ‘Headache’ in 20 lesser‑known drugs. Indian Journal of Research in Homoeopathy. 2019;13(1):4-11.

2. Gupta J, Manchanda RK, Chakraborty P, Singh P, Ramteke S, Singh O, et al. Prevalence and prognostic factor in patients with good therapeutic response in a cohort of 172 patients with the homoeopathic medicine Aranea diadema: A multicentre, open‑label, observational study. Indian Journal of Research in Homoeopathy. 2018;12(1):20-28.

3. Manchanda RK, Gupta J, Chakraborty P, Singh P, Nayan SS, Singh P, et al. Formic acid: A multicentric observational homoeopathic clinical verification trial. Indian Journal of Research in Homoeopathy. 2016;10(4):249-257.

4. Manchanda RK, Chakraborty P, Das KC, Rai MK, Singh O, et al. Symptom prevalence in a cohort of 147 patients improved with the homoeopathic medicine Ocimum canum: A multicenter, open, observational, clinical verification study. Indian Journal of Research in Homoeopathy. 2016;10(4):238-248.

5. Manchanda RK, Chakraborty P, Singh P, Pradhan PK, Prasad VG, Singh O, et al. A - multicenteric observational, homoeopathic clinical verification study of Cynodon dactylon revealing symptom prevalence in a cohort of 340 patients. Indian Journal of Research in Homoeopathy. 2016;10(4):225-237.

6. Manchanda RK, Chakraborty PS, Singh P, Nayan SS, Singh O, Pradhan PK, et al. Mygale lasiodora: A - multicentric observational homoeopathic clinical verification study. Indian Journal of Research in Homoeopathy. 2015;9(4):249-257.

7. Chakraborty PS, Kaushik S, Singh P, Nain SS, Singh O, Ramteke SS, et al. Assessing the therapeutic usefulness of Ricinus communis: A multicentric observational clinical verification study. Indian Journal of Research in Homoeopathy. 2014;8(4):200-208.

8. Chakraborty PS, Kaushik S, Nain SS, Singh P, Singh O, Das KC, et al. Clinical Verification of Ichthyolum - A multicentric observational study. Indian Journal of Research in Homoeopathy. 2012;6(4):24-33.

9. Chakraborty PS, Kaushik S, Nain SS, Singh P, Singh D, Singh O, et al. Staphylococcinum - A multicenter clinical verification study. Indian Journal of Research in Homoeopathy. 2012;6(2):15-21.

10. Chakraborty PS, Kaushik S, Nain SS, Singh P, Prasad VG, D Singh, et al. Alfalfa - A multicentric clinical verification study. Indian Journal of Research in Homoeopathy. 2011;5(3):36-43.

11. Chakraborty PS, Kaushik S, Ray RK, Yadav RP, Rai MK, Singh D, et al. Cassia fistula - A multicentric clinical verification study. Indian Journal of Research in Homoeopathy. 2011;5(2):20-29.

12. Chakraborty PS, Ali SA, Kaushik S, Ray RK, Yadav RP, Rai MK, et al. Curcuma longa - A multicentric clinical verification study. Indian Journal of Research in Homoeopathy. 2011;5(1):19-27.

13. Nayak C, Singh V, Singh K, Chakraborty PS, Kaushik, Ray RK et al, Tylophora indica - A multicentric clinical verification study. Indian Journal of Research in Homoeopathy. 2010;4(4):12-18.

14. Nayak C, Singh V, Singh K, Chakraborty PS, Kaushik, Ray RK, et al. Glycyrrhiza glabra - A muticentric clinical verification study. Indian Journal of Research in Homoeopathy. 2010;4(3):22-33.

9.4 Clinical Research

The institute has carried out Clinical Research trials on various disease conditions. The research methodology and the study designs of modern medicine have been considered to generate evidence-based outcomes. The acumen from these trial have been published in national and international journals of repute. The details of the ongoing and concluded studies of the institute are mentioned below.

9.4.1 Ongoing/assigned

Multimorbidity in older adults- RCT
Diabetes- RCT
Hypothyroidism-RCT
Allergic rhinitis-Comparative RCT
Primary dysmenorrhea-RCT
Irritable bowel syndrome-RCT
Acne- RCT
Randomized Controlled Trial on Early hemorrhoid disease
Randomized Controlled Trial on Chronic Suppurative Otitis Media
Scope of Homoeopathy in Menstrual distrubances in adolescent girls
Syzygium Jambolanum (DM)-RCT
Urticaria
NCD Survey

14. Management of Molluscum Contagiosum with Individualized Homoeopathy

15. Osteoarthritis

To be initiated

1. Progressive myopia-Comparative Trial

2. Scope of Ovarian Cyst in Homoeopathy

3. Stress in continuous of urine in elderly aged ladies

4. Micro nutrients disorder in school children

5. Homoeopathy in COPD

6. Abnormal vaginal discharge- Observational study

7. LR study of musculo skeletal disorders

8. Anal Fissure-RCT

9. Obesity with Hypothyroidism

10. Obese Children

11. NCD study

12. Hypertension

9.4.2 Concluded

Acute diarrhoeal diseases in children-observational study
Acute rhinitis in children- observational study
Acute otitis media-RCT
Adenotonsillar hypertrophy- observational study
Benign Prostatic Hypertrophy (BPH)-observational
Benign Prostatic Hypertrophy (BPH)-RCT
Breast Fibroadenoma-RCT
Cervical Spondylosis- RCT
Cervical spondylosis- pain management-RCT
Chronic Bronchitis-Observational
Chronic Non Specific Low Back Pain-RCT
Chronic sinusitis- observational study
Chronic sinusitis-RCT
Cough validation- acute and chronic- observational study
Cough validation -chronic -observational study
Distress during climacteric (menopausal) years-observational study
Dyslipidemia-RCT
Gastroenteritis-Observational study
Hypertension -RCT
Influenza like illness-RCT
Uterine fibroid-RCT
Iron deficiency Anemia in Children-RCT
Knee Osteoarthritis-RCT
Muriatic family study- observational study
NCD data collection study- observational study
Patient reported outcome measure study
Polycystic ovarian syndrome-RCT
Pre-Diabetes -RCT
Susceptibility Study- observational study
Sepia in menopause - RCT
Psoriasis - observational study
Psoriasis follow up study- observational study
Adeno Tonsillar Hypertrophy - observational study
Urolithiasis-observational study
Urolithiasis- RCT
Validation study on Acne- observational study
Tinea- observational study
Drug Utilization Evaluation- cross sectional survey
Validation study on Bronchial asthma- observational study
Vitiligo observational study-1- observational study
Vitiligo observational study -2- observational study
Vitiligo follow up study- observational study
Rubrics and medicine for acute condition using Vithoulkas compass- observational study
Warts-observational study
Rheumatoid Arthritis -observational study
Association between prophylactic AYUSH intervention and disease outcome in COVID-19 positive patients: A retrospective cohort study.
Impact of third wave of COVID-19 pandemic - cross sectional survey
Homoeopathic treatment of post COVID- 19 illnesses- open label exploratory multicentric study.
Management of Rheumatoid arthritis with individualized homoeopathy: An Observational study.
A multicentric clinical verification study of the drugs proved by the council with prognostic factor research: An open clinical trial- 8 drugs
Double Blind Placebo Controlled Trial on Warts
PCOS- non randomized comparative study
Old- vs. new method of preparation
UTI-RCT
IDA in school children- A Comparative three armed study
Public Health Program to assess prevalence of malnutrition in children aged between 6-18 years and adults aged more than 18 years and addressing them with homoeopathic intervention" under SCSP program

9.4.3 Achievements

(i) Research manuscripts published

Sl. No.	Study	Publication status
1.	Acute diarrhoeal diseases in children	C Nayak, Vikram Singh, K Singh, Hari Singh, Anita Sharma, Praveen Oberai, Varanasi Roja, Debadatta Nayak, Maya Padmanabhan, Alok Mishra, GC Sehegal, S Kaushik, CP Chowdhary, VK Singh, Sahid Ali, P Hima Bindu, DB Sarkar. A Prospective Multicentric Observational Study to Evolve the Usefulness of the Predefined Homoeopathic Medicines in the Management of Acute Diarrheal Disease in Children. American Journal of Homoeopathic Medicine, 2009; 102(3), Autum. Reprint in IJRH 2009; 3 (3): 21-28
2.	Acute rhinitis in children	Nayak C, Singh V, Singh K, Singh H, Oberai P, Roja V, Padmanabhan M, Prasad S, Arya MD, Mohanan PG, Singh O, John MD, Singh MBK, Bhagat SR, Ramteke S. A multi-centric open clinical trial to evaluate the usefulness of 13 predefined homeopathic medicines in the management of acute rhinitis in children. Int J High Dilution Res [online]. 2010 [cited YYYY Month dd]; 9(30):30-42.
3.	Acute otitis media	Roja Varanasi, Rupali Bhalerao; Paul Sumithran; Kiranmayee G. Rompicherla; Pramodji Singh; Sunil S. Ramteke; D. Karthikeyan,Dubashi Ramesh, Bhuvaneswari Subbarayalu, Shraddha Chauhan, Jayakrishnan Venugopal, Shravani Kampilli, Ajay Meena, Arvind Kumar, Viqar Ahmed Siddiqui, Praveen Oberai, Raj K. Manchanda. A Comparative Randomized Controlled Trial of Homeopathy versus Allopathy in Acute Otitis Media and Its Recurrence in Children. Complement Med Res (2025) 32 (2): 110–121.
4.	Adenotonsillar hypertrophy	Hima Bindu Ponnam , Roja Varanasi , Ratan Chandra Shil , Vinitha E. R. , Meetu Goel , Sunil Ramteke , D. Karthikeyan , D. D. Arya , Trupti Laxmi Swain , Navita Bagdi , Priyanka Srivastava , R. K. Manchanda , Praveen Oberai. Individualized Homeopathic Medicines in the Management of Symptomatic Adenotonsillar Hypertrophy in Children: A Prospective Observational Study. Homoepathy, 2024; 113(01): 032-040
5.	Benign Prostatic Hypertrophy (BPH)-observational	Praveen Oberai, Varanasi Roja, D. Ramesh, D. D. Arya, G. Ravi Chandra Reddy, S. K. Sharma, Chaturbhuja Nayak, Vikram Singh and Hari Singh. Homeopathic medicines in the management of Benign prostatic hyperplasia: A multi centric prospective observational study. Indian Journal of Research in Homoeopathy, 2012; 6(3):16-25.
6.	Benign Prostatic Hypertrophy (BPH)-RCT	Sharma B, Mehra P, Oberai P, Roja V, Reddy G, Arya DD, et al. Homoeopathic treatment for lower urinary tract symptoms in men with benign prostatic hyperplasia: An open label randomised multicentric placebo-controlled clinical trial. Indian J Res Homoeopathy 2018;12:113-24.
7.	Breast Fibroadenoma-RCT	Lamba CD, Oberai P, Wadhwa B, Parveen S, Soren A, Bhuvaneswari R, Pradhan PK, Shinde V, Gupta J. A Multi-Centric Single-Blind Randomized Placebo-Controlled Trial to Evaluate the Efficacy of the Individualized Homeopathic Intervention in Breast Fibroadenoma. OBM Integrative and Complementary Medicine. 2023 May;8(2):1-20.
8.	Cervical Spondylosis- RCT	C. Nayak, Vikram Singh, Jaya Gupta, Mohd. Shahid Ali, Ramendar Pal, M.D. Arya, P. Hima Bindu, Debadatta Nayak, Paromita Goswami. Homoeopathic individualized LM-potencies versus Centesimal potencies for pain management of cervical spondylosis: A multicenter prospective randomized exploratory clinical study. Indian Journal of Research in Homoeopathy, 2012; 6(4):16-23.
9.	Cervical spondylosis- pain management-RCT	Gupta J, Bawaskar R, Rao P, Shivadikar A, Sumithran P, Pal R, Ali S, Bindu H, Arya M D, Lamba CD, Kumar A, Kulshreshtha D. Homoeopathic therapy in cervical spondylosis pain management: A randomised, double-blind, placebo-controlled trial. Indian J Res Homoeopathy 2020;14:242-50
10.	Chronic Bronchitis-Observational	Jaya Gupta; M. Prakash Rao; Kolli Raju; RVR. Prasad; JS Arya; BK Mondal; Gopinadhan Sadanandan; Mohan Singh; Vikram Singh; Chaturbhuja Nayak; Abhishek Pramanik; Arvind Kumar ; Varanasi Roja. Management of early years of simple and mucopurulent chronic bronchitis with pre-defined homeopathic medicines – a Prospective Observational Study with 2-Years Follow-Up. International Journal of High Dilution Research 2019; 18(3-4):47-62
11.	Chronic sinusitis- observational study	Chaturbhuja Nayak, Vikram Singh1, VP Singh, Praveen Oberai, Varanasi Roja, Shashi Shekhar Shitanshu, MN Sinha, Deepti Deewan, BC Lakhera, Sunil Ramteke, Subhash Kaushik, Sarabjit Sarkar, NR Mandal, PG Mohanan, JR Singh, Sabyasachi Biswas and Georgekutty Mathew. Homeopathy in chronic sinusitis: a prospective multi-centric observational study. Homeopathy (2012) 101, 84-91
12.	Chronic rhinosinusitis-RCT	Praveen Oberai, Subhash Kaushik, Sunil Ramteke etal. A randomised, double-blind, placebo-controlled and parallel-arm trial to assess the effect of homoeopathic medicines on chronic rhinosinusitis. Vol. 17 (2023)
13.	Cough validation- acute and chronic	a) Lex Rutten, José Eizayaga, Harleen Kaur, Chetna Deep Lamba, Jyoti Sachdeva, Anil Khurana, Praveen Oberai, Rajkumar Manchanda, Sonia Raizada, Sujata Chaudhary, Vaishali Shinde, Vinitha Edavattath Ramanan, Chittaranjan Kundu, Pratha Pratim Pal, Rompicherla GR Kiranmayee, Amulya Ratan Sahoo, Bodankar Rajeshekhar, Ratan Chandra Shil, Nidhi Mahajan. Counting Polar Symptoms: How to Represent Results. Homeopathy 2021; 110(01): 027-035 b) Kaur H, Lamba CD, Sachdeva J, Rutten L, Khurana A, Oberai P, Manchanda RK, Raizada S, Chaudhury S, Ramanan VE, Shinde V, Kundu C, Pal PP, Kiranmayee RG, Sahoo AR, Rajeshekhar B, Shil RC, Mahajan N. Optimising the use of polar symptoms in Homoeopathy: Introduction to a pilot study of prognostic factor research in chronic cough. Indian J Res Homoeopathy 2020;14:200-10
14.	Cough validation -chronic	Kaur H, Rutten L, Rao S, Bajpai A, Lamba CD, Sachdeva J, Vinitha ER, Raizada S, Kiranmayee RG, Rajashekhar B, Kundu C. Homoeopathic treatment for chronic cough–a multicentric, prospective, exploratory trial. International Journal of High Dilution Research-ISSN 1982-6206. 2024 May 18;23(cf):146-60.
15.	Distress during climacteric (menopausal) years	Chaturbhuja Nayak , Vikram Singh, Krishna Singh, Hari Singh, Jaya Gupta, Chetna Deep Lamba, Anita Sharma, Bindu Sharma, Balachandran Indira, Subburayalu Bhuvaneshwari, Simran Kaur Bindra, Kunapuli Sree Venkata Bharata Luxmi. Management of Distress during Climacteric Years by Homoeopathic therapy. The Journal of Alternative & Complementary Medicine, 2011; 17 (11):1037-42
16.	Gastroenteritis	C Nayak, Vikram Singh, K Singh, Hari Singh, P S Chakraborty, Subhash Kaushik, Debadatta Nayak, Vinay Kumar, Maya Padmanabhan, Ramendra Pal, A K Tyagi, A K Bhakat5, L Debata and P K Kundu. A prospective multicentre observational study to evaluate the role of homeopathic therapy with a group of predefined homoeopathic medicines in the management of gastroenteritis. International Journal of Bio Research 2010; 1(2): 34-42. Reprint: IJRH 2011; 5(1): 28-35
17.	Hypertension	Varanasi R, Kolli R, Rai Y, Ramesh D, Kiranmayee R G, Chandra Reddy G R, Baig H, Patole T, Srivastava P, Bhalaerao R, Chaudhary A, Kumar A, Sarathy V, Jayasri G R, Sachdeva G, Jain SK, Sharma N, Amsole S, Oinam A, Oberai P, Manchanda RK. Effects of individualised homoeopathic intervention in Stage I essential hypertension: A single-blind, randomised, placebo-controlled trial. Indian J Res Homoeopathy 2020;14:3-14
18.	Influenza like illness	Chakraborty P S, Lamba C D, Nayak D, John M D, Sarkar D B, Poddar A, Arya J S, Raju K, Vivekanand K, Singh H B, Baig H, Prusty A K, Singh V, Nayak C. Effect of individualized homoeopathic treatment in influenza like illness: A multicenter, single blind, randomized, placebo controlled study. Indian J Res Homoeopathy 2013;7:22-30
19.	Uterine fibroid	Oberai P, Indira B, Varanasi R, Rath P, Sharma B, Soren A, Laxmi KB, Sharma A, Devi P, Padmanabhan M, Singh V, Nayak C. A multicentric randomized clinical trial of homoeopathic medicines in fifty millesimal potencies vis-à -vis centesimal potencies on symptomatic uterine fibroids. Indian J Res Homoeopathy 2016;10:24-35
20.	Iron deficiency Anemia in Children	Khurana A, Mittal R, Rath P, Moorthy K, Taneja D, Singh U, Mishra K, Manchanda RK. Ferrum phosphoricum 3X and Ferrum metallicum 3X in the treatment of iron deficiency anaemia in children: Randomized parallel arm study. Indian J Res Homoeopathy 2020; 14:171-8
21.	Polycystic ovarian syndrome-RCT	Lamba CD, Oberai P, Manchanda RK, Rath P, Bindu P H, Padmanabhan M. Evaluation of homoeopathic treatment in polycystic ovary syndrome: A single-blind, randomised, placebo-controlled pilot study. Indian J Res Homoeopathy 2018;12:35-45.
22.	Sepia in menopause - RCT	Jaya Gupta, Dimpi Kulshreshtha, Chetna Deep Lamba, Payal Gupta, Vaishali Shinde, Bharti Wadhwa, Arti Soren, J. S. Arya, Munmun Koley, Abhishek Pramanik, Suraia Parveen, Arvind Kumar. Homoeopathic medicine – Sepia for the management of menopausal symptoms: A multicentric, randomised, double-blind placebo-controlled clinical trial. Indian J Res Homoeopathy 2019;13:219-28.
23.	Psoriasis	Taneja, D., Sadhukhan, M., Rath, P., Sarangi MR etal. Open-Label Study to Evaluate the Response to Homeopathic Treatment of Psoriasis, OBM Integrative and Complementary Medicine 2022; 7(3), doi:10.21926/obm.icm.2203044
24.	Urolithiasis-observational study	VA Siddiqui, Hari Singh, Jaya Gupta, C Nayak, Vikram Singh, MN Sinha, AK Gupta, Paul Sumithran, Yogander Rai, Rajakumar, Rupali Dixit, Deepti Dewan. A multicentre observational study to ascertain the role of homoeopathic therapy in Urolithiasis. IJRH. 2011 ; 5( 2): 30-39
25.	Urolithiasis- RCT	Bhalerao R, Oberai P, Mehra P, Rai Y, Choubey G, Sahoo AR, Majumder A K, Sah M, Gupta A K, Tyagi A K, Siddiqui V A, Kumar A, Manchanda RK. Lycopodium clavatum for the management of urolithiasis: A randomised double blind placebo controlled trial. Indian J Res Homoeopathy 2019;13:139-49
26.	Vitiligo observational study-1	Chakraborty P S, Kaushik S, Debata L, Ram B, Kumar R, Shah M, Jha D K, Ramesh D, Padmanabhan M, Nayak C, Singh V. A multicentric observational study to evaluate the role of homoeopathic therapy in vitiligo. Indian J Res Homoeopathy 2015;9: 167-75
27.	Rubrics and medicine for acute conditions using Vithoulkas compass	Kaur H, Jain S, Katarmal D, Sachdeva J, Ponnam HB, Muraleedharan KC, Parveen S, Raizada S, Karso L, Bala R, Srivastava A. The Patient Population at Homeopathic Outpatient Clinics across India: A Clinical Data Collection Study. Homeopathy. 2024 May 31.
28.	Association between prophylactic AYUSH intervention and disease outcome in COVID-19 positive patients: A retrospective cohort study.	Chaudhary A, Nayak D, Pandey S, Shastri V, Kamble M, Pendse V, Prajapati V, Vaidya B, Rohit H, Beedmani S, Presswala N. Association between Usage of Prophylactic AYUSH Medicines and Disease Severity in COVID-19 Patients: A Retrospective Cohort Study. Homeopathy.
29.	Impact of third wave of COVID-19 pandemic on mental health and its related lifestyle: a cross sectional survey	Rath, P., Gautam, S., Jain, S., Bajpai, A., Singh, M., & Kaushik, S. Impact of third wave of COVID-19 pandemic on mental health and its related lifestyle: a cross sectional survey. International Journal Of Community Medicine And Public Health, 10(2), 766–775.
30.	Systematic review of usefulness of homeopathy for treatment of Polycystic Ovarian Syndrome.	Padmalaya Rath, Bindu Sharma, Priya Gautam, Pankhuri Misra. Systematic review of usefulness of homeopathy for treatment of Polycystic Ovarian Syndrome. PROSPERO 2021 CRD42021259208
31.	Efficacy of Homoeopathy in Polycystic Ovarian Syndrome-A Systematic Review	Rath, Padmalaya; Sharma, Bindu; Gautam, Priya; Misra, Pankhuri; Efficacy of homoeopathy in PCOS,Current Women's Health Reviews, Volume 20, Number 4, 2024, pp. 33-46(14)
32.	Homoeopathy vs. conventional primary care in children	Meenachem oberbaum. Anupriya Choudhary, Hima Bindu Ponnam, Reetha Krishnan, Dinesh V, Md Irfan, Debadatta Nayak, Swati Pandey et.al. Homoeopathy vs. conventional primary care in children during the first 24 months of life-a pragmatic randomized controlled trial: European Journal of Pediatrics: 2024 oct.; vol. 183, pg. 5455-5465.
33.	Rhino-Orbito-Cerebral Mucormycosis (ROCM)	Kaur H, Sachdeva J, Bawaskar R, Goyal T. Comparative Evaluation of Effectiveness of Standard of Care Alone and in Combination With Homoeopathic Treatment in COVID-19–Related Rhino-Orbito-Cerebral Mucormycosis (ROCM): Protocol for a Single Blind, Randomized Controlled Trial. JMIR Res Protoc 2025;14:e57905
34.	The Patient Population at Homeopathic Outpatient Clinics across India	Kaur H, Jain S, Katarmal D, Sachdeva J, Ponnam HB, Muraleedharan KC, Parveen S, Raizada S,etal. The Patient Population at Homeopathic Outpatient Clinics across India: A Clinical Data Collection Study. Homeopathy. 2024 May;114(2):74-84
35.	Cough	Kaur, H., Rutten, L., Rao, S., Bajpai, A., Lamba, C. D., Sachdeva, J., ER, V., Raizada, S., Kiranmayee, R. G., Rajashekhar, B., Kundu, C., Shinde, V., Choudhury, S., Sahoo, A. R., Shil, R. C., Chakma, A., Mahajan, N., Mishra, A., Khurana, A., Oberai, P., & Manchanda, R. K. (2024). Homoeopathic treatment for chronic cough – a multicentric, prospective, exploratory trial. International Journal of High Dilution Research - ISSN 1982-6206, 23(cf), 146–160.
36.	Homeopathic Prognostic Factor Research	Rutten L, Eizayaga JE, Kaur H, Rao S, Bajpai A, Lamba CD, Sachdeva J, R VE, Raizada S, Kiranmayee RG, Rajashekhar B, Kundu C, Shinde V, Choudhury S, Sahoo AR, Shil RC, Chakma A, Mahajan N, Mishra A, Khurana A, Oberai P, Manchanda RK. How to Assess Variation in Homeopathic Prognostic Factor Research? Homeopathy. 2025 May 30. doi: 10.1055/a-2544-2807. Epub ahead of print. PMID: 40446840.
37.	Dengue Fever	Debadatta Nayak, Lovepreet Kaur, Rupali Bhalerao, Karanpreet Nahar etal. Effectiveness of Eupatorium Perfoliatum 30C in Preventing Dengue Fever-A Prospective, Community-Based, Open Label, Parallel Cohort Study in Delhi, India. Homeopathy. 2024 Oct 24. doi: 10.1055/s-0044-1788663.

(ii) Other publications:

a) Case Series and Care Reports:

1. Rath P, Shukla I. Homoeopathic management of non-responsive, nodulocystic acne: A case report. Indian J Res Homoeopathy. 2023;17(2):173-180.

2. Rath P, Saraswat K. Management of ovarian cyst through Sepia in LM potency- two case reports. JISH. 2023;6(1):53-60.

3. Rath P, et al. Homoeopathy – An Alternative to Conventional Treatment for Infertility. Homœopathic Links. 2024;37(1):58–59.

4. Rath P, Mondal S, Thakur T. Management of Acne Vulgaris with Homeopathic Treatment – A Case Series. AYUHOM. 2023;10(2):90-98. doi: 10.4103/AYUHOM.AYUHOM_4_23.

5. Rath P, Wadhwa B, Saraswat K, Singh A. Management of Ovarian Cysts through Individualized Homoeopathic Medicine: A Case Series. Homœopathic Links. 2024.

6. Rath P, Jana SN. Responding to Disaster Health Needs with Homoeopathy. Disaster: Response & Management J. 2023;10(1):28-42.

7. Rath P, Jana SN, Nayak C, Saraswat K. Prerequisites for novice researchers to conduct clinical research. J Ayurved Homeopath Allied Health Sci. 2023;2(1):25-30.

8. Nahar K, Kaushik S. Homoeopathy for management of type 2 diabetes mellitus in a patient of major depressive disorder - A case report. Indian J Res Homoeopathy 2021;15 (1):55-61.

9. Padmalaya Rath, Harleen Kaur. A case of haemorrhoid in a 12yrs child. 2014 IJRH,vol.8,issue.1: 37-41.

10. Rath P. Management of PCOS through Homoeopathy-A case report. Indian J Res Homoeopathy, 2018; 12 (2):95-100.

11. Rath P, Goswami A; A Case of Infertility with PCOD treated with Non Invasive Homoeopathy. Advancement in Homoeopathic Research, 2018; 3 (2): 23-26.

12. Padmalaya Rath, Shruti Jain. A case of secondary infertility with uterine fibroid treated with Homoeopathic medicine. IJRAR, 2019; l6 (2): 1013-1021.

13. Padmalaya Rath, Bhopal Singh Arya, Anil Kumar Vichitra, Udaiveer Singh. Case Series of Dengue Treated with Homoeopathic Intervention. 2019, Homœopathic Links, 32 (1): 31-35.

14. Amiya Goswami, Rath P. Homoeopathic approach in infertility and PCOD. Scholarly Research journal for interdisciplinary studies; 7 (45): 67-71.

15. Rath P, Parul. Homoeopathic treatment of chronic urticaria – A case series. Indian J Res Homoeopathy 2020;14 (4):267-78.

16. Rath P, Gautam S. Homoeopathic Management in a Case of Infertility with PCOS. Homoeopathic link. 2021; 34 (2): 148-152.

17. Padmalaya Rath. A Case of Acne Vulgaris Treated with Homoeopathy, Clinical Images. Homoeopathic Links 2020;33(3):244.

18. Rath P. A case of infertility due to PCOS treated successfully with homoeopathy. International Journal of Homoeopathic Sciences 2020; 4(2): 249-260.

19. Wadhwa B. A case report of fibroadenosis alleviated with Homoeopathy. Indian J Res Homoeopathy 2017;11 (3):196-202.

20. Sonia Raizada. Catheter removed with homoeopathy in patient of benign prostatic hypertrophy and renal calculus: A case report. International Journal of Homoeopathic Sciences. 2019; 3 (4): 9-15.

21. Punam Kumari. Hemorrhagic ovarian cyst treated with constitutional Homoeopathy: A case report. 2020 International Journal of Homoeopathic Sciences, 4 (4 part C): 143-147.

22. Punam Kumari. Management of leiomyoma with lesser known medicine Aurum Muriaticum Natronatum: a case report. 2021 International Journal of AYUSH, 10 (1):23-34.

23. Kaur H, Singh R. Infantile haemangioma treated with Homoeopathy: A case report. Indian J Res Homoeopathy 2024;18:78-85.

24. Punam Kumari, Verma R. Nephrotic syndrome treated with homoeopathy: An evidence-based case-report. Indian J Res Homoeopathy 2022; 16(3). doi: 10.53945/2320-7094.1047

25. Punam Kumari. Uterine Fibroid Treated with Homoeopathic Medicine: A Case Report. Homœopathic Links. 2022; 35. 205-209. 10.1055/s-0042-1742592.

26. Punam Kumari, Shivam Kumar, Renu Verma. Management of tinea corporis with the minimum doses of homoeopathic nosode Psorinum: A case report. Indian J Res Homoeopathy 2024;18:86-91.

27. Punam Kumari, Shivam Kumar, Renu Verma. Healing of Haemorrhoidal Disease with Homoeopathy – A Case Series. Homœopathic Links. 2024; 10.1055/s-0042-1755531.

28. Raizada S, Shukla I. A Survey Report on Rise in Respiratory Illnesses Due to Air Pollution and Its Homoeopathic Management. Homœopathic Links. 2021 Dec;34(04):278-82.

29. Raizada S. Homoeopathic management of polycystic ovarian syndrome–A case series. Indian Journal of Research in Homoeopathy. 2022;16(3):7.

30. Raizada S, Shukla I. Complete Resolution of Peptic Ulcer by Individualised Homoeopathic Anti-Miasmatic Treatment—A Case Report. Homœopathic Links. 2023 Mar;36(01):069-72.

31. Raizada S, Shukla I. Human Cystic Echinococcosis Treated with Individualised Homoeopathy—A Case Report. Homœopathic Links. 2024 Nov 11.

32. KBD Kumar, P Rath, T Thakur, Homoeopathic Management of Male Infertility – A Case Series, Homoeopathic Links 36(12)

33. Rath , P.et al.A Case of Uterine Fibroid Associated with Gallbladder Polyp Treated with Homoeopathy;Homœopathic Links

34. Rath P. Management of PCOS through Homoeopathy-A case report. Indian J Res Homoeopathy 2018;12:95-100.

35. Raj K. Manchanda, Anupriya Chaudhary, Swati Pandey, Altunay Agaoglu. Modernization and Standardization of Homoeopathic Education Globally: A LMHI Initiative: Homoeopathy for all 2024 July; vol 26, no.7 (292) pg 29-33.

36. Kaur H, Jain S, Katarmal D, Sachdeva J, Ponnam HB, Muraleedharan KC, Parveen S, Raizada S, Karso L, Bala R, Srivastava A, Shinde V, Ramteke S, Choubey G, Kundu C, Ramanan VE, Patole T, Sonny R, Bhattacharjee B, Sardarla RK, Bawaskar RS, Reddy GRC, Avinash KK, Tamang S, Prusty AK, Sadhukhan M, Maglara A, Garoufali A, Stassinopoulos M, Lilas T, Tapakis L, Khurana A, Manchanda RK. The Patient Population at Homeopathic Outpatient Clinics across India: A Clinical Data Collection Study. Homeopathy. 2024 May;114(2):74-84.

37. Rinku Bishwas, Karanpreet Nahar etal. A Homoeopathic Case Study on Urolithiasis: Management with Constitutional Treatment. African Journal of Biomedical Research. September 2024 Vol. 27 .

38. Debadatta Nayak, Lovepreet Kaur, Rupali Bhalerao, Karanpreet Nahar etal. Effectiveness of Eupatorium Perfoliatum 30C in Preventing Dengue Fever- A Critical Appraisal.Feb 2025 doi: 10.1055/s-0044-1801390.

39. Homoeopathic management of Verruca Vulgaris- A case series accepted in will be published in upcoming AYUHOM

40. Rath P, Gautam P, Goswami AD, Jana SN.Polycystic ovarian syndrome and homoeopathic management: Acase series.Indian J Res Homoeopathy 2024;18:200-211.

41. Rutten L, Eizayaga JE, Kaur H, Rao S, Bajpai A, Lamba CD, Sachdeva J, ER V, Raizada S, Kiranmayee RG, Rajashekhar B. How to assess variation in homeopathic prognostic factor research?. Homeopathy. 2025 May 30.

42. Kaur H, Jain S, Katarmal D, Sachdeva J, Ponnam HB, Muraleedharan KC, Parveen S, Raizada S, Karso L, Bala R, Srivastava A. The patient population at homeopathic outpatient clinics across India: a clinical data collection study. Homeopathy. 2025 May;114(02):074-84.

b) Books/Monographs (Contribution in content development):

1. H. Baig, K. Singh, A. Sharma, P. Oberai, S. Kaushik, D. Nayak, A. Mishra. Role of Cephalandra indica Q in the management of Diabetes Mellitus as an add on medicine along with conventional antidiabetics. CCRH’s Clinical Research Studies (series-II), 2010, pg.15-20.

2. H. Baig, K. Singh, A. Sharma, S. Kaushik, A. Mishra. Rhus aromaticus in the management of Diabetes mellitus, CCRH’s Clinical Research Studies (series-II), 2010, pg.21-27.

3. H. Baig, K. Singh, A. Sharma, S. Kaushik, A. Mishra, Suniti Chugh. Essential hypertension, CCRH’s Clinical Research Studies (series-II), 2010, pg.29-41.

4. B. C. Lakhera, I. M. Dhawan, Manjushree, S. Kaushik, A. Mishra, Suniti Chugh. Essential hypertension (Drug related study), CCRH’s Clinical Research Studies (series-II), 2010, pg.43-49.

5. R. V. R. Prasad, Ch. Raveender, B. Lakshmi, K. Singh, A. K. Vichitra, P. Oberai, R. Mittal. Clinical evaluation of predefined homoeopathic medicine in Vitiligo, CCRH’s Clinical Research Studies (series-II), 2010, pg.85-92.

6. Anita Sharma, Praveen Oberai, Subhash Kaushik, Padmalaya Rath, Shashi Sekhar Sitanshu. Acute respiratory infections, CCRH’s Clinical Research Studies (series-III), 2010, pg.1-9.

7. A. Sharma, P. Oberai, D. Nayak, S. S. Shitanshu. Dysentery, CCRH’s Clinical Research Studies (series-III), 2010, pg.10-16.

8. A. Sharma, P. Oberai, S. Kaushik, S. Parveen, K. Vivekanand, S. S. Shitanshu. Paediatric diarrhea, CCRH’s Clinical Research Studies (series-III), 2010, pg.36-41.

9. A. Sharma, P. Oberai, S. Kaushik, K. Vivekanand, J. Sachdeva, S. S. Shitanshu. Tonsillitis, CCRH’s Clinical Research Studies (series-III), 2010, pg.54-62.

10. Padmalaya Rath. Dysmenorrhea. Standard Treatment guidelines- volume -2, Central Council for Research in Homoeopathy. New Delhi- 2018.pg no. 69-80.

11. Sonia Raizada. Insomnia disorder. Standard Treatment guidelines- volume -2, Central Council for Research in Homoeopathy. New Delhi- 2018.pg no. 135-148.

12. Kusum S. Chand, Bindu Sharma, Pritha Mehra. Disease Monograph – Bronchial Asthma. Chapter 4 : Prescribing strategy. CCRH’s publication, 2015, pp. 207-281.

13. Pritha Mehra, Pooja Pandey. Sciatica syndrome. Standard Treatment guidelines- volume -3, Central Council for Research in Homoeopathy. New Delhi- 2021. Pg. no.209-218.

14. Shweta Gautam, Amenorrhoea. Standard Treatment guidelines- volume -4, Central Council for Research in Homoeopathy. New Delhi- 2023. Pg. no 33-49.

15. Study of Homoeopthic medicine through Clinical verification, Vol. 5,Central Council for Research in Homoeopathy. New Delhi-2021, Pg.1-300

16. Study of Homoeopathic medicine through Clinical verification, Vol. 6,Central Council for Research in Homoeopathy. New Delhi-2023

17. Contribution in book titled- “Study of Homoeopathic Medicines through Clinical Verification – A new perspective”, volume 5 and 6.

18. पद्मालय रथ , आयुषी, केन्द्रीय होम्योपैथी अनुसंधान संस्थान , आयुष मंत्रालय, हिंदी पखवाड़ा 2017

19. बांझपन का होम्योपैथिक इलाज, नोएडा स्वार, 9वां संस्कारणे, 2023

20.Padmalaya Rath and Dr. Shib Narayan Jana. Responding to Disaster Health Needs with Homoeopathy. Disaster: Response & Management Journal Vol X No. 1 (ISSN: 2347-2553): p28-42

c) Review Article

1. S. Kaushik. Review draft: Homoeopathy in treatment of type II Diabetes Mellitus – Journal of Homoeopathy University, Annual Homoeopathic Journal, Volume 2, Issue April 2016, pg. 63-68.

2. Karanpreet Nahar, Subhash Kaushik. Role of a Homoeopathic physician in Modern scenario. Homoeopathic Medical Association Magazine of Muzaffarnagar, Uttar Pradesh. 2018, pg. 97-98.

3. Subhash Kaushik. Karanpreet Nahar. Homoeopathic Case Series writing– An Overview Article, Journal of Homoeopathy University, Annual Homoeopathic Journal, Volume 4, issue April 2019, pg. 43-47.

4. सुभाष कौशिक. हिंदी पत्रिका “आयुषी”, केंद्रीय होम्योपैथी अनुसंधान परिषद् वर्ष 2017, लेख “हिंदी का शब्द-भण्डार”, प्रष्ठ सं 4-5.

5. सुभाष कौशिक. हिंदी पत्रिका “आरोही”, केंद्रीय होम्योपैथी अनुसंधान परिषद् वर्ष 2019, लेख “स्वच्छ भारत”, प्रष्ठ सं 21-23.

6. सुभाष कौशिक. हिंदी पत्रिका “ सृष्टि”, राष्ट्रीय होम्योपैथी मानसिक स्वास्थ्य अनुसंधान संस्थान , कोट्टायम, केरल, वर्ष 2020, लेख “हिंदी का शब्द-भण्डार”, प्रष्ठ सं 24-25.

7. Padmalaya Rath. Book review on Invertabrates in Homoeopathy. Homoeopathic link, 2020;33: (1) 59.

8. Rath P, Jana S. A Brief Account of Homoeopathic Approach to Fight COVID-19 Disaster; review article. Homoeopathic Links, 2020, 33 (3): 147-152.

9. S.N. Jana, Padmalaya Rath. Rediscovery of Materia medica- Abrotanum. e-newsletter, Vol. III, Homoepathic pulse, ejournal of Delhi govt, 2014.

10. S. N. Jana, Padmalaya Rath. Rediscovery of Materia medica- Acetic acid. e-newsletter; Vol. V, Homoepathic pulse, ejournal of Delhi govt, 2014.

11. S. N. Jana, Padmalaya Rath. Rediscovery of Materia medica- Aconite napellus. e-newsletter; Vol. VI, Homoepathic pulse, ejournal of Delhi govt, 2015.

12. Padmalaya Rath. Chapter Reproductive Health; “Orientation Guideline for Doctors in respect of Homoeopathy”. CCRH, Ministry of AYUSH, 2020.

13. Pritha Mehra. Short Communication: Usefulness of homeopathy in essential hypertension: an exploratory interventional trial. International Journal of High Dilution Research. 2015; 14(1):16-19.

14. Pankhuri Misra, Pritha Mehra. Memoir: Dr. Christian Friedrich Samuel Hahnemann (1755–1843). Homœopathic Links 2020, 33 (02), 076-077.

15. Karanpreet Nahar. Lessons learnt from the Spanish Flu pandemic. Indian Journal of Research in Homoeopathy. 2020. 14: 295-296.

16. Solanki A, Nahar K, Meena H. Artificial intelligence in healthcare: Have We Made the transition from fiction to reality? International Journal of Advanced Medical and Health Research. 2019. 6(2):39.

17. Karanpreet Nahar, Chautubhuja Nayak. Review of Literature for Dissertation: Why and How?. Advancements in Homoeopathy Research. 2023. 8(1): 28-32.

18. Komal Prajapati, Karanpreet Nahar. Implications of physiological action of Calendula officinalis to understand its guiding symptoms. International Journal of Research Health and Allied Sciences. 2021.

19. Komal Prajapati, Karanpreet Nahar. A lesser-known Homoeopathic remedy to combat ill-effects from post COVID illness. International Journal of Research Health and Allied Sciences. 2021.

20. Tridibesh Tripathy, Shankar Das, Umakant Prusty, Chintamani Nayak, Lipipuspa Devata, Padmalaya Rath etal. Exercise, Diet, Homoeopathy- a Healing Triad of Resistant Hypertension; East African Scholars J Med Sci;, 6(5), 147-152.

21. Manchanda RK, Anupriya, Pandey Swati; Altunany Agaoglu; Modernization and standardization of Homoeopathic Education Globally; Homoeopathy for all, July 2024, Vol 26 no.7,ISSN 0973-9823.

22. Rath, Padmalaya; Sharma, Bindu; Gautam, Priya; Misra, Pankhuri; Efficacy of homoopathy in PCOS,Current Women's Health Reviews, Volume 20, Number 4, 2024, pp. 33-46(14)

23. Rath P, Jana SN, Nayak C, Saraswat K. Prerequisites for novice researchers to conduct clinical research. J Ayurved Homeopath Allied Health Sci 2023; 2:25-30.

24. Singh, Kirti, Upadhyay, Ashok Kumar and Singh, Shiv (2020). “Research Output of Indian Scholars on Anemia: A bibliometric analysis”. Elementary Education Online, 2020; Vol 19 (Issue 3): pp. 4756-4768

25. Singh, Shiv, Singh, Kirti & Munjal, N (2021). "Global Research Output on First Principles: A Scientometric study". In (Eds) Tarsem Lal "Emerging Trends in Academic Libraries in ICT Era", Saptrishi Publications, Chandigarh, 61-7p. ISBN: 978-93-906-76-2.

26. Singh, Kirti, Upadhyay, Ashok Kumar and Singh, Shiv (2021). “Indian Research Trends in Thalassemia: A bibliometric study”. International Journal of Biology, Pharmacy and Allied Sciences, Special Issue, 2021, 10(12): pp.81-89.

27. Singh, Kirti, Upadhyay, Ashok Kumar and Singh, Shiv (2022). “Indian Research Trends on Leukemia: Evidence from PubMed”. Virtual International Conference on Library and Information Science (VICLIS-2022), Conf. Proc., pp.14.

28. Mukhrjee, Maitri, Upadhyay, Ashok Kumar and Singh, Shiv and Singh, Kirti (2022) “A scientometric examination of Oceanography research in India” Information, Knowledge &Research: Changing Role of Libraries ICAL-2022, 123-127.

29. Singh, Shiv, Singh Kirti, Ahmed J, Soni VM, Munjal N (2022). "Research and Development of Biomass Production in India: A Bibliometric Study." Advances in Functional and Smart Materials: Select Proceedings of ICFMMP 2021. Singapore: Springer Nature Singapore,. 161-173.

30. Singh, Shiv, Soni, Vijay Mohan Singh, Kirti, and Munjal, Neha (2023). “Research Output on Ecological Awareness: A Bibliometric Survey 2009-2018”. Proceedings of the International Conference on Materials for Emerging Technologies, AIP Conf. Proc. 2800, pp. 020312-1–020312-7.

31. Singh, Shiv,Singh Kirti, Mishra, Reena, Soni, Vijay Mohan and Munjal, Neha (2023). “Global research on medical physics: Evidence from WOS”. 3rd National Conference on Recent Advancement in Physical Sciences (NCRAPS-2021), AIP Conf. Proc. 2728, pp. 040009-1–040009-10.

32. Singh, Kirti, Upadhyay, Ashok Kumar and Singh, Shiv (2023). “Indian Publications Trend in Coagulation Research: Evidence from Pubmed”. 3rd International Conference of the Central Government Library Association (CGLA), Conf. Proc., pp.28-33.

9.5. Other Activities

a) Projects under National Health Programme

b) Schedule Caste Sub Plan Health Camps: Organization of Health Camps in SC dominated villages & conducting public health programs:

● Concluded: Public Health Program to assess prevalence of malnutrition in children aged between 6-18 years and adults aged more than 18 years and addressing them with homoeopathic intervention" under SCSP program.

● Ongoing: Patient satisfaction survey at rural outreach medical camps OPD: a cross-sectional survey.

● To be initiated: Public health program to assess the prevalence of Vitamin-D deficiency and its management with homoeopathic medicine.

● Organization of Health Camps in SC dominated villages. - Ongoing

● Azadi ka Amrit Mahotsav. - Concluded

b) Professional outreach activities

● Continuing Medical Education

● Seminars

● Workshops

● Health Camps

● Health Melas / Exhibitions

● Inviting Indian & Foreign delegations to visit the centre

Academic tours and training of students of different Homoeopathic Medical Colleges.

Future Vision

Upgrading the existing infrastructure to that of a Centre of Excellence for Drug Development

Development of any Medical system depends on the four core sectors namely Medical Education, Research, Drug Development and Patient care services.

a) The unique strength of DDPRCRI (H) Noida is in the area of Drug development. Since inception, it has been working in the area of Drug Standardization with an output of 20 publications in peer reviewed journals and contribution in around 20 books published by the Council. The centre has developed Pathology, Biochemistry, Molecular Biology, Pharmacognosy, Physico-Chemical Laboratory, Pharmacology and Zebra Fish Lab. In addition to ANIMAL HOUSE which needs to be adequately equipped with state of the art machinery and man power as per CPSCEA guidelines to develop it in to a National Institute of Excellence. The proposed In-house Pharmacy shall be a boon in providing health care delivery to common man in a cost effective manner. It would also prove to be a milestone in the development of new drugs and carry out their safety and efficacy studies and evolve their pharmacological action.

It is proposed to have an In House Pharmacy with the following infrastructure:

● Raw drug storage room- Air curtain, passing bench, Mirror, side raw drug storage, space for shoe wrapping machine, lab coat hanger and sanitizer stand.

● Trituration room- 2-Triturator machine platform, Metal transparent cupboards for chemicals, triturates, toxic chemicals and lactose, Center work bench, and Weighing Balance platform.

● Mother Tincture room- Platform for segregation and drying of plant drugs; Platform for Weighing Balance, Chopper, Mixer Grinder, Sieving assembly, Transparent metal cupboard for glassware ,etc, Work Bench at center, Platform for Hot Air Oven and Percolator assembly, DM and purified water supply.

● Potentization room .- Antivibration table with noise proof wall for 3 potentizers, ,Exit door , Tablet machine space, Work Bench for Dilutions, DM and purified water supply, Transparent metal cupboard for glassware ,etc.

● Packaging room - Bottle capping and sealing machine, Packaging bench , Transparent metal cupboards, Label printing machine.

● Documentation room -Transparent metal cupboards, Racks for documentation of COA certificates for chemicals ,raw drug authenticity certificates, MT certificate, IPQC records, BMR records, and other file work.

b) The Outpatient Department (OPD) attracts about 400-450 patients daily and has a 50 bedded hospital with about 70% bed occupancy. The OPD and IPD are open to general cases and these patients can be utilized as a good research resource. The institute provides various laboratory facilities. The institute is presently equipped with radiological department with the facilities of Digital X-ray machine and ultrasonography machine.

c) Introduction of academic program. The institute proposes to have PhD in Materia Medica and Pharmacy. Introduction of academic programme will need the signing of MoU with Academic institutions.

When it is developed into a National Homoeopathy Drug Research Institute with a special focus on Drug Development, it will be beneficial to public, students, teachers, industry and researchers. The proposed National Institute shall have the prime mandate of filling the gaps that exist in the field of Drug Standardisation, Drug proving and Clinical verification in Homoeopathy. The institute is expected to set benchmarks in academics, research and health care for other institutions in Homoeopathy in India and abroad.

DELIVERABLES

The core objectives of the institute will be the following:-

(i) Setting quality control parameters and manufacturing processes of Homoeopathic medicines and products

(ii) Preparation and Potentization of new drugs and evaluation of their pharmacological activity

(iii) Development of Human Resources with interdisciplinary and integrated teaching & training

(iv) To develop state of art Pathology, Biochemistry, Pharmacology and Molecular Biology Labs for developing new drugs in Homoeopathy.

(v) To provide effective and free health care services at the grass root level in a cost effective way.

(vi) Reaching out to people to create awareness about the scope of Homoeopathy among the masses.

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