Publication
The Regional Research Institute for Homoeopathy (RRIH), Shimla, functioning under the Central Council for Research in Homoeopathy (CCRH), Ministry of AYUSH, Government of India, has been a prominent contributor to clinical research, clinical verification, and evidence-based public health initiatives in the field of Homoeopathy. Since its inception, the institute has actively engaged in collaborative and institutional projects, supported by its dedicated scientific personnel.
I. Clinical Research Projects (Institutional & Collaborative)
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Title
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Duration
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Details
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Uterine Fibroid
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June 2009 – Nov 2011
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Oberai P. et al. A multicentric randomized clinical trial of homoeopathic medicines in fifty millesimal potencies vis-à-vis centesimal potencies on symptomatic uterine fibroids. IJRH 2016; 10(1):25–34.
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Influenza Like Illness
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June 2009 – Dec 2010
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Chakraborty PS et al. Effect of individualized homoeopathic treatment in influenza like illness: a multicenter, single blind, randomized, placebo-controlled study. IJRH 2013; 7:22–30.
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Chronic Sinusitis (Observational)
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2005 – 2010
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Sharma SR et al. Clinical evaluation of homoeopathic medicines in sinusitis. IJRH 2008; 2(1):26–37.
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Chronic Rhinosinusitis (RCT)
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2012 – 2014
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Study protocol published: IJRH 2014; 8(3):123–28. Manuscript under preparation.
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Urolithiasis (RCT)
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2012 – 2015
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Data collection completed. Manuscript under review.
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Acute Otitis Media (RCT)
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Nov 2014 – Nov 2018
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235 children enrolled out of 396 screened. Data under analysis.
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II. Clinical Verification Studies (CCRH Multicentric Programs)
A. Clinical Verification of 23 Drugs (2010–2014)
Published in Indian Journal of Research in Homoeopathy:
· Iris tenax, Glycyrrhiza glabra, Tylophora indica, Curcuma longa, Cassia fistula, Alfalfa, Staphylococcinum, Ichthyolum, Ricinus communis.
B. Clinical Verification of 16 Drugs (2014–2018)
· Mygalela siodora, Cynodon dactylon, Ocimum canum, Formic acid, Mangifera indica, Aranea diadema, and exploratory analysis on predictive symptoms (e.g., headache in lesser-known drugs).
C. Clinical Verification of 08 Drugs
Conducted under the ongoing CCRH verification program; manuscripts are under preparation and review.
D. Clinical Verification of 10 drugs (ongoing)-
Clinical Verification of 10 Homoeopathic Drugs: A Multicentric Prospective Interventional Single-Arm Clinical Trial.
III. Other Scientific Contributions.
A. Clinical Trials & Observational Research
1. Prajapati R, Saklani N, Biswas A. Utility of Boenninghausen’s Characteristics and Repertory by C. M. Boger in the treatment of acne vulgaris – An open-label, single arm, clinical trial. National Homoeo Recorder 2019;15(4):21-27.
2. Parewa M, Burman AS, Brahma A, Rutten L, Sadhukhan S, Misra P, Gupta B, Saklani N, Michael J, Basu A, Ali SS. Individualized homeopathic medicines in the treatment of generalized anxiety disorder: A double-blind, randomized, placebo-controlled, pilot trial. Complementary Medicine Research. 2021 Mar 4;28(5):407-18.Psoralea corylifolia as an add-on in vitiligo – Pragmatic pilot trial.https://doi.org/10.1159/000514524
3. Srikanth N, Kumar A, Chandrasekhararao B, Singhal R, Yadav B, Khanduri S, Jameela S, Rai AK, Tripathi A, Rana R, Ahmad A. Disease characteristics, care-seeking behavior, and outcomes associated with the use of AYUSH-64 in COVID-19 patients in home isolation in India: A community-based cross-sectional analysis. Frontiers in public health. 2022 Jul 6;10:904279.https://doi.org/10.3389/fpubh.2022.904279
4. Dutta, Abhijit; Bhakta, Puja1; Mir, Anaitulah Ahmed2; Singh, Suman; Saprunamei, Athia Sylvia2; Prajapati, Ramkripal3; Pandey, Deepak Kumar3; Anal, Ch. Lily4; Saklani, Nitin3; Goenka, Rachna1; Singh, Subhas; Chattopadhyay, Abhijit2; Sharma, Pralay5; Sadhukhan, Satarupa; Ali, Sk Swaif6; Koley, Munmun7; Saha, Subhranil8. Factor Structure of the Bengali Version of the Fagerstrom Test for Nicotine Dependence Questionnaire: A Cross-Sectional Study. Indian Journal of Social Psychiatry 37(3):p 319-327, Jul–Sep 2021.http://dx.doi.org/10.4103/ijsp.ijsp_71_20
5. Saklani NK, Prajapati, R. Utility of Kent's Repertory in the treatment of candidiasis: An open labelled, Single arm, interventional clinical trial. Int J High Dilution Res [Internet].2024 Mar. 14[cited 2024 Mar. 15]; 23 (cf): 16https://doi.org/10.51910/ijhdr.v23icf.1294
6. Add-on Psoralea corylifolia mother tincture external application to individualized homoeopathic medicines in treatment of vitiligo: Open, randomized, pragmatic, pilot trial.https://doi.org/10.1016/j.aimed.2021.03.003
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B. Public Health & Clinical Insights
7. Nayak D, Nahar K, Kaur L, Singh S, Ponnam HB, Rawat BS, Prusty AK, Prusty U, Karso L, Debata L, Goli SP. Adherence to Prophylactic Use of Homeopathic Arsenicum album during COVID-19 in India: A Cross-Sectional Study in 23 Cities. Homeopathy. 2025 Oct 7. https://doi.org/10.1055/a-2636-4424
8. Concurrent Utilization and Medication Adherence of Arsenicum album 30C as Prophylactic Against COVID-19: A Cross-Sectional, Community-Based Study. https://doi.org/10.1055/s-0046-1817115
9. Post-COVID complications – Managed through “Swiftly, Safely and Sweetly” approach.https://spaka.in/post-covid-19-complication-and-their-management-through-swiftly-safely-and-sweetly-mode-of-treatment-homoeopathy.html
10. Hot water epilepsy – Homoeopathic case management.https://spaka.in/hot-water-epilepsy-its-clinical-presentation-and-management-through-swiftly-safely-and-sweetly-mode-of-treatment-homoeopathy.html
11. Dengue – Prevention and therapeutic approach via Homoeopathy.https://spaka.in/dengue-its-clinical-presentation-and-management-through-homeopathy.html
12. COVID 19 its battle to survive along with human beings in this ecosystem: and its management through "Swiftly, Safely and Sweetly" Mode of treatment- Homoeopathy.https://spaka.in/covid-19-its-battle-to-survive-along-with-human-beings-in-this-ecosystem-and-its-management-through-swiftly-safely-and-sweetly-mode-of-treatment-homoeopathy-2.html
C. Research Methodology & Reviews
13. Saklani NK. Nayak C. Writing effective introduction: Why and how. The Homoeopathic Heritage. Volume 49. No. 3. June 2023. Page No. 24.
14. Saklani N. Verma B. Unveiling the current landscape of clinical Research in Homoeopathy- where do we stand. Vol. 49. No. 8. November 2023. 59-66.
15. Saklani NK. “Exploring the potential of Homoeopathy: A detailed examination of Systematic Review and Meta- analysis procedure- weighing the Pros and Cons”. Int J High Dilution Res [Internet]. 2024 Apr. 21 ;23(cf):61-73. Available from:https://www.highdilution.org/index.php/ijhdr/article/view/1406
16. Saklani N. Hypertension: Detection, Evaluation and Its Managment. The Homoeopathic Heritage. Vol. 49, No. 7, October 2023. 68-72.
D. Case Reports & Evidence-Based Outcomes
17. Management of Lichen planus nodularis through indiviudalized Homoeopathy – A Case report.https://doi.org/10.70805/ija-care.v8i4.643
18. Management of Geographic tongue with individualized Homoeopathy – Evidence-based case report.https://doi.org/10.1055/s-0044-1782224
19. Saklani NK, Verma D, Verma B. Reviving hope: a homeopathic triumph over pancreatic necrosis with ascites: evidence-based case report. Homœopathic Links. 2025 Jun 10.https://doi.org/10.1055/s-0045-1806846
20. Verma D, Saklani N. Plantar psoriasis treated with homoeopathic medicine: An evidence-based case report. J Integr Stand Homoeopath. 2026;9:38-43. doi: 10.25259/JISH_4_2025
21. Verma D, Saklani NK, Kumar A. Holistic approach of Homoeopathy in treatment of multimorbidity: A case report. Indian J Res Homoeopathy. 2026;20(1):87–96. https://doi.org/10.53945/2320-7094.2112
22. Saklani NK. Homoeopathic intervention in dual autoimmune disorders: A case report on management of vitiligo and hashimoto thyroiditis. Indian J Res Homoeopathy. 2025;19(4):451–60.https://doi.org/10.53945/2320-7094.2024
23. Saklani NK. Resolution of Epidermal Inclusion Cyst through Homeopathic Treatment: An Evidence-Based Case Report. Homœopathic Links. 2025 Dec;38(04):207-10. DOI: 10.1055/s-0045-1809969
24. Saklani NK, Verma B. Successful discontinuation of levothyroxine in a known case of hypothyroidism through personalised homoeopathic treatment: An evidence-based case report. J Integr Stand Homoeopath. 2025;8:143-52. doi: 10.25259/JISH_6_2025.